Comparison of biological activities of Glycyrrhiza glabra and G. uralensis
The biological activities of Glycyrrhiza (GLs) extracts (GL-1, Glycyrrhiza glabra from Eumseong, Korea; GL-2, G. uralensis from Eumseong, Korea; GL-3, G. uralensis from Yeongcheon, Korea; GL-4, G. uralensis from Neimenggu, China: GL-5, G. uralensis purchased from Korea Medicine Herbal Assoc...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Belgrade, University of Novi Sad
2014-01-01
|
| Series: | Archives of Biological Sciences |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641404431P.pdf |
| Summary: | The biological activities of Glycyrrhiza (GLs) extracts (GL-1, Glycyrrhiza
glabra from Eumseong, Korea; GL-2, G. uralensis from Eumseong, Korea; GL-3,
G. uralensis from Yeongcheon, Korea; GL-4, G. uralensis from Neimenggu,
China: GL-5, G. uralensis purchased from Korea Medicine Herbal Association,
Korea) were investigated. G. uralensis (GLs-2, -3, -4, and -5) extracts
exhibited higher free radical scavenging activity against DPPH and OH
radicals than G. glabra (GL-1). In addition, all GLs had antibacterial
activity against E. coli, S. aureus, and H. pylori. GL-3 inhibited the growth
of E. coli and S. aureus, while GL-1 had antibacterial activity against H.
pylori. All GL extracts tested inhibited the lipopolysaccharide- and
interferon-γ-induced inflammatory activity of RAW 264.7 cells. G. glabra and
G. uralensis reduced NO generation. GL-3 also inhibited the growth of AGS
human gastric adenocarcinoma cells. GLs-3 and -4 showed the inhibition of rat
lens aldose reductase. GL-4 had a higher total content of glycyrrhizin (1),
glycyrrhetinic acid (2), glabridin (3), and isoliquiritigenin (4). G.
uralensis (GLs-2, -3, -4, and -5) is thus more effective than G. glabra
(GL-1). |
|---|---|
| ISSN: | 0354-4664 1821-4339 |