Comparison of biological activities of Glycyrrhiza glabra and G. uralensis
The biological activities of Glycyrrhiza (GLs) extracts (GL-1, Glycyrrhiza glabra from Eumseong, Korea; GL-2, G. uralensis from Eumseong, Korea; GL-3, G. uralensis from Yeongcheon, Korea; GL-4, G. uralensis from Neimenggu, China: GL-5, G. uralensis purchased from Korea Medicine Herbal Assoc...
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| Format: | Article |
| Language: | English |
| Published: |
University of Belgrade, University of Novi Sad
2014-01-01
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| Series: | Archives of Biological Sciences |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641404431P.pdf |
| _version_ | 1819136473249611776 |
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| author | Park Chun-Geon Lee Ah Young Lee Jeong Min Lee Sang-Hoon Lee Jeong Hoon Choi Ae Jin Park Chung Berm Cho Ju Eun Lee Sanghyun |
| author_facet | Park Chun-Geon Lee Ah Young Lee Jeong Min Lee Sang-Hoon Lee Jeong Hoon Choi Ae Jin Park Chung Berm Cho Ju Eun Lee Sanghyun |
| author_sort | Park Chun-Geon |
| collection | DOAJ |
| description | The biological activities of Glycyrrhiza (GLs) extracts (GL-1, Glycyrrhiza
glabra from Eumseong, Korea; GL-2, G. uralensis from Eumseong, Korea; GL-3,
G. uralensis from Yeongcheon, Korea; GL-4, G. uralensis from Neimenggu,
China: GL-5, G. uralensis purchased from Korea Medicine Herbal Association,
Korea) were investigated. G. uralensis (GLs-2, -3, -4, and -5) extracts
exhibited higher free radical scavenging activity against DPPH and OH
radicals than G. glabra (GL-1). In addition, all GLs had antibacterial
activity against E. coli, S. aureus, and H. pylori. GL-3 inhibited the growth
of E. coli and S. aureus, while GL-1 had antibacterial activity against H.
pylori. All GL extracts tested inhibited the lipopolysaccharide- and
interferon-γ-induced inflammatory activity of RAW 264.7 cells. G. glabra and
G. uralensis reduced NO generation. GL-3 also inhibited the growth of AGS
human gastric adenocarcinoma cells. GLs-3 and -4 showed the inhibition of rat
lens aldose reductase. GL-4 had a higher total content of glycyrrhizin (1),
glycyrrhetinic acid (2), glabridin (3), and isoliquiritigenin (4). G.
uralensis (GLs-2, -3, -4, and -5) is thus more effective than G. glabra
(GL-1). |
| first_indexed | 2024-12-22T10:35:32Z |
| format | Article |
| id | doaj.art-e86b269eb0fd476d90efc9b42cf2e0ed |
| institution | Directory Open Access Journal |
| issn | 0354-4664 1821-4339 |
| language | English |
| last_indexed | 2024-12-22T10:35:32Z |
| publishDate | 2014-01-01 |
| publisher | University of Belgrade, University of Novi Sad |
| record_format | Article |
| series | Archives of Biological Sciences |
| spelling | doaj.art-e86b269eb0fd476d90efc9b42cf2e0ed2022-12-21T18:29:12ZengUniversity of Belgrade, University of Novi SadArchives of Biological Sciences0354-46641821-43392014-01-016641431143910.2298/ABS1404431P0354-46641404431PComparison of biological activities of Glycyrrhiza glabra and G. uralensisPark Chun-Geon0Lee Ah Young1Lee Jeong Min2Lee Sang-Hoon3Lee Jeong Hoon4Choi Ae Jin5Park Chung Berm6Cho Ju Eun7Lee Sanghyun8National Institute of Horticultural & Herbal Science, Department of Herbal Crop Research, Eumseong, Republic of KoreaPusan National University, Department of Food Science and Nutrition, Busan, Republic of KoreaNational Institute of Horticultural & Herbal Science, Department of Herbal Crop Research, Eumseong, Republic of Korea + Chung-Ang University, Department of Integrative Plant Science, Anseong, Republic of KoreaNational Institute of Horticultural & Herbal Science, Department of Herbal Crop Research, Eumseong, Republic of KoreaNational Institute of Horticultural & Herbal Science, Department of Herbal Crop Research, Eumseong, Republic of KoreaNational Institute of Horticultural & Herbal Science, Department of Herbal Crop Research, Eumseong, Republic of KoreaNational Institute of Horticultural & Herbal Science, Department of Herbal Crop Research, Eumseong, Republic of KoreaPusan National University, Department of Food Science and Nutrition, Busan, Republic of KoreaChung-Ang University, Department of Integrative Plant Science, Anseong, Republic of KoreaThe biological activities of Glycyrrhiza (GLs) extracts (GL-1, Glycyrrhiza glabra from Eumseong, Korea; GL-2, G. uralensis from Eumseong, Korea; GL-3, G. uralensis from Yeongcheon, Korea; GL-4, G. uralensis from Neimenggu, China: GL-5, G. uralensis purchased from Korea Medicine Herbal Association, Korea) were investigated. G. uralensis (GLs-2, -3, -4, and -5) extracts exhibited higher free radical scavenging activity against DPPH and OH radicals than G. glabra (GL-1). In addition, all GLs had antibacterial activity against E. coli, S. aureus, and H. pylori. GL-3 inhibited the growth of E. coli and S. aureus, while GL-1 had antibacterial activity against H. pylori. All GL extracts tested inhibited the lipopolysaccharide- and interferon-γ-induced inflammatory activity of RAW 264.7 cells. G. glabra and G. uralensis reduced NO generation. GL-3 also inhibited the growth of AGS human gastric adenocarcinoma cells. GLs-3 and -4 showed the inhibition of rat lens aldose reductase. GL-4 had a higher total content of glycyrrhizin (1), glycyrrhetinic acid (2), glabridin (3), and isoliquiritigenin (4). G. uralensis (GLs-2, -3, -4, and -5) is thus more effective than G. glabra (GL-1).http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641404431P.pdfdiseasefood industrylicoricenatural component |
| spellingShingle | Park Chun-Geon Lee Ah Young Lee Jeong Min Lee Sang-Hoon Lee Jeong Hoon Choi Ae Jin Park Chung Berm Cho Ju Eun Lee Sanghyun Comparison of biological activities of Glycyrrhiza glabra and G. uralensis Archives of Biological Sciences disease food industry licorice natural component |
| title | Comparison of biological activities of Glycyrrhiza glabra and G. uralensis |
| title_full | Comparison of biological activities of Glycyrrhiza glabra and G. uralensis |
| title_fullStr | Comparison of biological activities of Glycyrrhiza glabra and G. uralensis |
| title_full_unstemmed | Comparison of biological activities of Glycyrrhiza glabra and G. uralensis |
| title_short | Comparison of biological activities of Glycyrrhiza glabra and G. uralensis |
| title_sort | comparison of biological activities of glycyrrhiza glabra and g uralensis |
| topic | disease food industry licorice natural component |
| url | http://www.doiserbia.nb.rs/img/doi/0354-4664/2014/0354-46641404431P.pdf |
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