Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation

Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation

(1) Background: Successful treatment of acute kidney injury (AKI)-induced chronic kidney disease (CKD) is unresolved. We aimed to characterize the time-course of changes after contralateral nephrectomy (Nx) in a model of unilateral ischemic AKI-induced CKD with good translational utility. (2) Method...

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Bibliographic Details
Main Authors: Pál Tod, Eva Nora Bukosza, Beáta Róka, Tamás Kaucsár, Attila Fintha, Tibor Krenács, Gábor Szénási, Péter Hamar
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
acute kidney injury
chronic kidney disease
inflammation
MCP-1
TNF-α
mice
Online Access:https://www.mdpi.com/1422-0067/21/11/3825

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