Folate-Targeted PEGylated Magnetoliposomes for Hyperthermia-Mediated Controlled Release of Doxorubicin

Folate-Targeted PEGylated Magnetoliposomes for Hyperthermia-Mediated Controlled Release of Doxorubicin

Doxorubicin (DOX) is a chemotherapeutic agent commonly used for the treatment of solid tumors. However, the cardiotoxicity associated with its prolonged use prevents further adherence and therapeutic efficacy. By encapsulating DOX within a PEGylated liposome, Doxil® considerably decreased DOX cardio...

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Bibliographic Details
Main Authors: Emílio R. Cintra, Tacio G. Hayasaki, Ailton A. Sousa-Junior, Artur C. G. Silva, Marize C. Valadares, Andris F. Bakuzis, Sebastião A. Mendanha, Eliana M. Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
magnetoliposomes
doxorubicin
magnetic hyperthermia
folic acid
B16F10
MCF7
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.854430/full

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