The metabolomics of psoriatic disease
Di Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics&rdq...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2017-01-01
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| Series: | Psoriasis: Targets and Therapy |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-metabolomics-of-psoriatic-disease-peer-reviewed-article-PTT |
| _version_ | 1818839440444882944 |
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| author | Yan D Afifi L Jeon C Trivedi M Chang HW Lee K Liao W |
| author_facet | Yan D Afifi L Jeon C Trivedi M Chang HW Lee K Liao W |
| author_sort | Yan D |
| collection | DOAJ |
| description | Di Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics. Keywords: metabolome, psoriasis, psoriatic arthritis, skin, urine, metabolites |
| first_indexed | 2024-12-19T03:54:20Z |
| format | Article |
| id | doaj.art-e8724ac9a9f74989a8b34e1b4f6a1544 |
| institution | Directory Open Access Journal |
| issn | 2230-326X |
| language | English |
| last_indexed | 2024-12-19T03:54:20Z |
| publishDate | 2017-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Psoriasis: Targets and Therapy |
| spelling | doaj.art-e8724ac9a9f74989a8b34e1b4f6a15442022-12-21T20:36:51ZengDove Medical PressPsoriasis: Targets and Therapy2230-326X2017-01-01Volume 711531079The metabolomics of psoriatic diseaseYan DAfifi LJeon CTrivedi MChang HWLee KLiao WDi Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics. Keywords: metabolome, psoriasis, psoriatic arthritis, skin, urine, metaboliteshttps://www.dovepress.com/the-metabolomics-of-psoriatic-disease-peer-reviewed-article-PTTMetabolomePsoriasisPsoriatic arthritisSkinUrineMetabolites |
| spellingShingle | Yan D Afifi L Jeon C Trivedi M Chang HW Lee K Liao W The metabolomics of psoriatic disease Psoriasis: Targets and Therapy Metabolome Psoriasis Psoriatic arthritis Skin Urine Metabolites |
| title | The metabolomics of psoriatic disease |
| title_full | The metabolomics of psoriatic disease |
| title_fullStr | The metabolomics of psoriatic disease |
| title_full_unstemmed | The metabolomics of psoriatic disease |
| title_short | The metabolomics of psoriatic disease |
| title_sort | metabolomics of psoriatic disease |
| topic | Metabolome Psoriasis Psoriatic arthritis Skin Urine Metabolites |
| url | https://www.dovepress.com/the-metabolomics-of-psoriatic-disease-peer-reviewed-article-PTT |
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