Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report
Histiocytic Sarcoma (HS) is a rare malignant neoplasm characterised by the neoplastic proliferation of cells showing morphological and immunophenotypic features of mature histiocytes. Majority of the reported cases present in extranodal sites, such as the head and neck, thyroid, duodenum, small in...
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JCDR Research and Publications Private Limited
2023-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/18180/64031_CE[Ra1]_F(IS)_PF1(SD_OM_RD_IS)_PFA(HJ_KM)_PN(KM).pdf |
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| author | Maneesh kumar Vijay Neha Sethi Lalit Mohan Sharma Sanjay Sharma |
| author_facet | Maneesh kumar Vijay Neha Sethi Lalit Mohan Sharma Sanjay Sharma |
| author_sort | Maneesh kumar Vijay |
| collection | DOAJ |
| description | Histiocytic Sarcoma (HS) is a rare malignant neoplasm characterised by the neoplastic proliferation of cells showing morphological
and immunophenotypic features of mature histiocytes. Majority of the reported cases present in extranodal sites, such as the head
and neck, thyroid, duodenum, small intestine, colon, urinary bladder, spleen, and leptomeninges. This report documents a case of
primary involvement of the salivary gland by HS. A 77-year-old male patient presented with a firm swelling in the left submandibular
region for the last three months. Multiple lymph nodes, along with the presence of lung and liver nodules, were seen. Thus the final
diagnosis of HS was made based on histopathology and IHC. Palliative chemotherapy was given to the patient, responded well,
and has been well for the last year. The present study is probably the first case of HS involving the submandibular gland. |
| first_indexed | 2024-03-12T20:58:32Z |
| format | Article |
| id | doaj.art-e8787a1934154da9bcde55b06bc45b92 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-12T20:58:32Z |
| publishDate | 2023-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-e8787a1934154da9bcde55b06bc45b922023-07-31T11:22:16ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-07-01177070910.7860/JCDR/2023/64031.18180Histiocytic Sarcoma of Submandibular Gland: A Rare Case ReportManeesh kumar Vijay0Neha Sethi1Lalit Mohan Sharma2Sanjay Sharma3Assistant Professor, Department of Oncopathology, Mahatma Gandhi Medical College, Sitapura Industrial Area, Jaipur, Rajasthan, India.Assistant Professor, Department of Oncopathology, Mahatma Gandhi Medical College, Sitapura Industrial Area, Jaipur, Rajasthan, India.Assistant Professor, Department of Medical OncologyMahatma Gandhi Medical College, Sitapura Industrial Area, Jaipur, Rajasthan, India.Assistant Professor, Department of Surgical Oncology, Mahatma Gandhi Medical College, Sitapura Industrial Area, Jaipur, Rajasthan, India.Histiocytic Sarcoma (HS) is a rare malignant neoplasm characterised by the neoplastic proliferation of cells showing morphological and immunophenotypic features of mature histiocytes. Majority of the reported cases present in extranodal sites, such as the head and neck, thyroid, duodenum, small intestine, colon, urinary bladder, spleen, and leptomeninges. This report documents a case of primary involvement of the salivary gland by HS. A 77-year-old male patient presented with a firm swelling in the left submandibular region for the last three months. Multiple lymph nodes, along with the presence of lung and liver nodules, were seen. Thus the final diagnosis of HS was made based on histopathology and IHC. Palliative chemotherapy was given to the patient, responded well, and has been well for the last year. The present study is probably the first case of HS involving the submandibular gland.https://www.jcdr.net/articles/PDF/18180/64031_CE[Ra1]_F(IS)_PF1(SD_OM_RD_IS)_PFA(HJ_KM)_PN(KM).pdfcd 68histiocyteslymphomasalivary gland |
| spellingShingle | Maneesh kumar Vijay Neha Sethi Lalit Mohan Sharma Sanjay Sharma Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report Journal of Clinical and Diagnostic Research cd 68 histiocytes lymphoma salivary gland |
| title | Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report |
| title_full | Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report |
| title_fullStr | Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report |
| title_full_unstemmed | Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report |
| title_short | Histiocytic Sarcoma of Submandibular Gland: A Rare Case Report |
| title_sort | histiocytic sarcoma of submandibular gland a rare case report |
| topic | cd 68 histiocytes lymphoma salivary gland |
| url | https://www.jcdr.net/articles/PDF/18180/64031_CE[Ra1]_F(IS)_PF1(SD_OM_RD_IS)_PFA(HJ_KM)_PN(KM).pdf |
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