Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease

Marek’s disease virus (MDV) can cause malignant T-cell lymphomas and immunosuppression in chickens. Macrophage migration inhibitory factor (MIF) not only plays a critical role in inhibiting T-cell responses, but also contributes to multiple aspects of tumour progression. The aim of this study was to...

Full description

Bibliographic Details
Main Authors: Fan Zhongjun, Wang Huanli, Pan Jiahao, Yu Shupei, Xia Wenlong
Format: Article
Language:English
Published: Sciendo 2020-01-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2020-0009
_version_ 1819038199157096448
author Fan Zhongjun
Wang Huanli
Pan Jiahao
Yu Shupei
Xia Wenlong
author_facet Fan Zhongjun
Wang Huanli
Pan Jiahao
Yu Shupei
Xia Wenlong
author_sort Fan Zhongjun
collection DOAJ
description Marek’s disease virus (MDV) can cause malignant T-cell lymphomas and immunosuppression in chickens. Macrophage migration inhibitory factor (MIF) not only plays a critical role in inhibiting T-cell responses, but also contributes to multiple aspects of tumour progression. The aim of this study was to reveal the potential role of MIF in the pathogenesis of MDV infection.
first_indexed 2024-12-21T08:33:31Z
format Article
id doaj.art-e87dad75a2e74c61b4c295ee7e3c5224
institution Directory Open Access Journal
issn 2450-8608
language English
last_indexed 2024-12-21T08:33:31Z
publishDate 2020-01-01
publisher Sciendo
record_format Article
series Journal of Veterinary Research
spelling doaj.art-e87dad75a2e74c61b4c295ee7e3c52242022-12-21T19:10:08ZengSciendoJournal of Veterinary Research2450-86082020-01-01641333810.2478/jvetres-2020-0009jvetres-2020-0009Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s diseaseFan Zhongjun0Wang Huanli1Pan Jiahao2Yu Shupei3Xia Wenlong4College of Marine and Biological Engineering, Yancheng Teachers’ University, Yancheng224002, ChinaCollege of Marine and Biological Engineering, Yancheng Teachers’ University, Yancheng224002, ChinaCollege of Marine and Biological Engineering, Yancheng Teachers’ University, Yancheng224002, ChinaCollege of Marine and Biological Engineering, Yancheng Teachers’ University, Yancheng224002, ChinaCollege of Marine and Biological Engineering, Yancheng Teachers’ University, Yancheng224002, ChinaMarek’s disease virus (MDV) can cause malignant T-cell lymphomas and immunosuppression in chickens. Macrophage migration inhibitory factor (MIF) not only plays a critical role in inhibiting T-cell responses, but also contributes to multiple aspects of tumour progression. The aim of this study was to reveal the potential role of MIF in the pathogenesis of MDV infection.https://doi.org/10.2478/jvetres-2020-0009marek’s disease virusmacrophage migration inhibitory factorchicken embryo fibroblastspathogenesis
spellingShingle Fan Zhongjun
Wang Huanli
Pan Jiahao
Yu Shupei
Xia Wenlong
Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
Journal of Veterinary Research
marek’s disease virus
macrophage migration inhibitory factor
chicken embryo fibroblasts
pathogenesis
title Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
title_full Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
title_fullStr Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
title_full_unstemmed Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
title_short Potential role of macrophage migration inhibitory factor in the pathogenesis of Marek’s disease
title_sort potential role of macrophage migration inhibitory factor in the pathogenesis of marek s disease
topic marek’s disease virus
macrophage migration inhibitory factor
chicken embryo fibroblasts
pathogenesis
url https://doi.org/10.2478/jvetres-2020-0009
work_keys_str_mv AT fanzhongjun potentialroleofmacrophagemigrationinhibitoryfactorinthepathogenesisofmareksdisease
AT wanghuanli potentialroleofmacrophagemigrationinhibitoryfactorinthepathogenesisofmareksdisease
AT panjiahao potentialroleofmacrophagemigrationinhibitoryfactorinthepathogenesisofmareksdisease
AT yushupei potentialroleofmacrophagemigrationinhibitoryfactorinthepathogenesisofmareksdisease
AT xiawenlong potentialroleofmacrophagemigrationinhibitoryfactorinthepathogenesisofmareksdisease