Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran
<p>Abstract</p> <p>Background</p> <p>Vancomycin-resistant entrococci (VRE) are increasing in prevalence at many institutions, and are often reported in dialysis patients. The aim of this cross-sectional prevalence study was to determine the prevalence and risk factors o...
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| Format: | Article |
| Language: | English |
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BMC
2007-06-01
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| Series: | BMC Infectious Diseases |
| Online Access: | http://www.biomedcentral.com/1471-2334/7/52 |
| _version_ | 1818530696561426432 |
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| author | Stadler Maria Askarian Mehrdad Assadian Ojan Shaghaghian Soheila |
| author_facet | Stadler Maria Askarian Mehrdad Assadian Ojan Shaghaghian Soheila |
| author_sort | Stadler Maria |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Vancomycin-resistant entrococci (VRE) are increasing in prevalence at many institutions, and are often reported in dialysis patients. The aim of this cross-sectional prevalence study was to determine the prevalence and risk factors of VRE colonization in chronic hemodialysis patients in two hemodialysis centers in Shiraz, Iran.</p> <p>Methods</p> <p>Rectal swabs were obtained from all consenting patients and were streaked on the surface of Cephalexin-aztreonam-arabinose agar (CAA) and incubated at 37°C in air for 24 h. The vancomycin susceptibility of each isolate was confirmed by disk susceptibility testing. The MICs of vancomycin and teicoplanin were confirmed by the E test. To identify risk factors, a questionnaire was completed for all the studied patients and the data of VRE positive and negative groups were compared using Man-Withney U test for continues data and the Fisher exact test for categorical data.</p> <p>Results</p> <p>Of 146 patients investigated, 9 (6.2%) were positive for VRE. All VRE strains were genotypically distinguishable. Risk factors for a VRE-positive culture were "antimicrobial receipt within 2 months before culture" (P = 0.003) and "hospitalization during previous year" (P = 0.016).</p> <p>Conclusion</p> <p>VRE colonization is an under-recognized problem among chronic dialysis patients in Iran. VRE colonization is associated with antibiotic consumption and hospitalization.</p> |
| first_indexed | 2024-12-11T17:22:59Z |
| format | Article |
| id | doaj.art-e8815fe07d904cfcafec214b12afc747 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-11T17:22:59Z |
| publishDate | 2007-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-e8815fe07d904cfcafec214b12afc7472022-12-22T00:57:04ZengBMCBMC Infectious Diseases1471-23342007-06-01715210.1186/1471-2334-7-52Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, IranStadler MariaAskarian MehrdadAssadian OjanShaghaghian Soheila<p>Abstract</p> <p>Background</p> <p>Vancomycin-resistant entrococci (VRE) are increasing in prevalence at many institutions, and are often reported in dialysis patients. The aim of this cross-sectional prevalence study was to determine the prevalence and risk factors of VRE colonization in chronic hemodialysis patients in two hemodialysis centers in Shiraz, Iran.</p> <p>Methods</p> <p>Rectal swabs were obtained from all consenting patients and were streaked on the surface of Cephalexin-aztreonam-arabinose agar (CAA) and incubated at 37°C in air for 24 h. The vancomycin susceptibility of each isolate was confirmed by disk susceptibility testing. The MICs of vancomycin and teicoplanin were confirmed by the E test. To identify risk factors, a questionnaire was completed for all the studied patients and the data of VRE positive and negative groups were compared using Man-Withney U test for continues data and the Fisher exact test for categorical data.</p> <p>Results</p> <p>Of 146 patients investigated, 9 (6.2%) were positive for VRE. All VRE strains were genotypically distinguishable. Risk factors for a VRE-positive culture were "antimicrobial receipt within 2 months before culture" (P = 0.003) and "hospitalization during previous year" (P = 0.016).</p> <p>Conclusion</p> <p>VRE colonization is an under-recognized problem among chronic dialysis patients in Iran. VRE colonization is associated with antibiotic consumption and hospitalization.</p>http://www.biomedcentral.com/1471-2334/7/52 |
| spellingShingle | Stadler Maria Askarian Mehrdad Assadian Ojan Shaghaghian Soheila Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran BMC Infectious Diseases |
| title | Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran |
| title_full | Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran |
| title_fullStr | Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran |
| title_full_unstemmed | Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran |
| title_short | Prevalence of Vancomycin-Resistant Enterococci colonization and its risk factors in chronic hemodialysis patients in Shiraz, Iran |
| title_sort | prevalence of vancomycin resistant enterococci colonization and its risk factors in chronic hemodialysis patients in shiraz iran |
| url | http://www.biomedcentral.com/1471-2334/7/52 |
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