Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique
Abstract Background Left ventricular-arterial coupling is assessed as the ratio of left ventricular end-systolic elastance (Ees) to arterial elastance (Ea). Previous studies have introduced non-invasive estimations of Ees/Ea. It requires only four variables, namely pre-ejection period, ejection time...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-02-01
|
| Series: | BMC Anesthesiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12871-024-02452-6 |
| _version_ | 1797273497470238720 |
|---|---|
| author | Yurie Obata Yuka Matsuki Kazuhiro Okafuji Kenji Shigemi |
| author_facet | Yurie Obata Yuka Matsuki Kazuhiro Okafuji Kenji Shigemi |
| author_sort | Yurie Obata |
| collection | DOAJ |
| description | Abstract Background Left ventricular-arterial coupling is assessed as the ratio of left ventricular end-systolic elastance (Ees) to arterial elastance (Ea). Previous studies have introduced non-invasive estimations of Ees/Ea. It requires only four variables, namely pre-ejection period, ejection time, end-systolic pressure and diastolic pressure. The aims of the present study were to clarify the reference values of Ees/Ea estimated using the noninvasive technique, and to investigate the effects of age and gender on Ees/Ea in healthy subjects. Methods This retrospective study utilized data from healthy, 30-79-year-old subjects. We recorded electrocardiogram, phonocardiogram, and brachial arterial pulse waves simultaneously using the vascular screening system, and used the observed variables to calculate Ees/Ea. We separated subjects into five groups according to their age and compared Ees/Ea among the different age groups. Results The study included 2114 males and 2292 females. Ees/Ea ranged from 1.87 to 2.04 in males, and 1.98 to 2.32 in females. We observed no age-related differences in Ees/Ea in males (p = 0.10), and significant differences in females (p < 0.001). Ees/Ea in males was not different compared to those in females in 60-69-year-old group (p = 0.92). Whereas Ees/Ea was higher in females compared to those in males in the other age groups. The differences between medians of Ees/Ea in males and those in females were 0.45 (p < 0.001), 0.24 (p < 0.001), 0.13 (p = 0.01), and 0.13 (p = 0.03) in 30–39, 40–49, 50–59, and 70-79-year-old age groups, respectively. Conclusions We clarified the reference values of Ees/Ea in healthy subjects. The effect of age on Ees/Ea is different in males and females, although Ees/Ea is maintained within a relatively narrow range in all subjects. |
| first_indexed | 2024-03-07T14:45:11Z |
| format | Article |
| id | doaj.art-e88661200e9d4cc39ec4918ec77a7ad5 |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-03-07T14:45:11Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-e88661200e9d4cc39ec4918ec77a7ad52024-03-05T20:04:45ZengBMCBMC Anesthesiology1471-22532024-02-012411610.1186/s12871-024-02452-6Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive techniqueYurie Obata0Yuka Matsuki1Kazuhiro Okafuji2Kenji Shigemi3Department of Anesthesiology, Yodogawa Christian HospitalDepartment of Anesthesiology and Reanimatology, Faculty of Medicine Sciences, University of FukuiHealth Examination Center, Fukui-ken Saiseikai HospitalDepartment of Anesthesiology and Reanimatology, Faculty of Medicine Sciences, University of FukuiAbstract Background Left ventricular-arterial coupling is assessed as the ratio of left ventricular end-systolic elastance (Ees) to arterial elastance (Ea). Previous studies have introduced non-invasive estimations of Ees/Ea. It requires only four variables, namely pre-ejection period, ejection time, end-systolic pressure and diastolic pressure. The aims of the present study were to clarify the reference values of Ees/Ea estimated using the noninvasive technique, and to investigate the effects of age and gender on Ees/Ea in healthy subjects. Methods This retrospective study utilized data from healthy, 30-79-year-old subjects. We recorded electrocardiogram, phonocardiogram, and brachial arterial pulse waves simultaneously using the vascular screening system, and used the observed variables to calculate Ees/Ea. We separated subjects into five groups according to their age and compared Ees/Ea among the different age groups. Results The study included 2114 males and 2292 females. Ees/Ea ranged from 1.87 to 2.04 in males, and 1.98 to 2.32 in females. We observed no age-related differences in Ees/Ea in males (p = 0.10), and significant differences in females (p < 0.001). Ees/Ea in males was not different compared to those in females in 60-69-year-old group (p = 0.92). Whereas Ees/Ea was higher in females compared to those in males in the other age groups. The differences between medians of Ees/Ea in males and those in females were 0.45 (p < 0.001), 0.24 (p < 0.001), 0.13 (p = 0.01), and 0.13 (p = 0.03) in 30–39, 40–49, 50–59, and 70-79-year-old age groups, respectively. Conclusions We clarified the reference values of Ees/Ea in healthy subjects. The effect of age on Ees/Ea is different in males and females, although Ees/Ea is maintained within a relatively narrow range in all subjects.https://doi.org/10.1186/s12871-024-02452-6Ventricular-arterial couplingEnd-systolic elastanceArterial elastanceNon-invasiveAgeGender |
| spellingShingle | Yurie Obata Yuka Matsuki Kazuhiro Okafuji Kenji Shigemi Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique BMC Anesthesiology Ventricular-arterial coupling End-systolic elastance Arterial elastance Non-invasive Age Gender |
| title | Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique |
| title_full | Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique |
| title_fullStr | Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique |
| title_full_unstemmed | Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique |
| title_short | Effect of age and gender on ventricular-arterial coupling estimated using a non-invasive technique |
| title_sort | effect of age and gender on ventricular arterial coupling estimated using a non invasive technique |
| topic | Ventricular-arterial coupling End-systolic elastance Arterial elastance Non-invasive Age Gender |
| url | https://doi.org/10.1186/s12871-024-02452-6 |
| work_keys_str_mv | AT yurieobata effectofageandgenderonventriculararterialcouplingestimatedusinganoninvasivetechnique AT yukamatsuki effectofageandgenderonventriculararterialcouplingestimatedusinganoninvasivetechnique AT kazuhirookafuji effectofageandgenderonventriculararterialcouplingestimatedusinganoninvasivetechnique AT kenjishigemi effectofageandgenderonventriculararterialcouplingestimatedusinganoninvasivetechnique |