Comparative transcriptional profiling of regenerating damaged knee joints in two animal models of the newt Notophthalmus viridescens strengthens the role of candidate genes involved in osteoarthritis

Comparative transcriptional profiling of regenerating damaged knee joints in two animal models of the newt Notophthalmus viridescens strengthens the role of candidate genes involved in osteoarthritis

Objectives: To compare joint regeneration in adult newts (N. viridescens) upon both newly established surgical removal and previously reported enzymatic destruction of articular cartilage to identify molecular factors and functionally analyze potentially important regulators involved in osteoarthrit...

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Bibliographic Details
Main Authors: Matthias Geyer, Christiane Schönfeld, Carina Schreiyäck, Sony A. Susanto, Christian Michel, Mario Looso, Thomas Braun, Thilo Borchardt, Elena Neumann, Ulf Müller-Ladner
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Regeneration
Osteoarthritis
Cartilage
Species
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913122000413

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