Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager

We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and...

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Main Authors: Taylor Wintler, Monica Zherebtsov, Susanne Carmack, Rebecca Muntean, Sarah J. Hill
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Journal of Pediatric Surgery Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213576621003249
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author Taylor Wintler
Monica Zherebtsov
Susanne Carmack
Rebecca Muntean
Sarah J. Hill
author_facet Taylor Wintler
Monica Zherebtsov
Susanne Carmack
Rebecca Muntean
Sarah J. Hill
author_sort Taylor Wintler
collection DOAJ
description We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child.
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spelling doaj.art-e8897498a49143bdb5d6ae9303e4a7a12022-12-21T23:13:20ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662021-12-0175102103Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenagerTaylor Wintler0Monica Zherebtsov1Susanne Carmack2Rebecca Muntean3Sarah J. Hill4Washington State University, Elson S. Floyd College of Medicine, Spokane, WA, USAPediatric Gastroenterology Providence Digestive Health Institute, Spokane, WA, USAIncyte Diagnostics, Spokane, WA, USAProvidence Rheumatology Providence Health and Services, Spokane, WA, USAProvidence Sacred Heart Medical Center Pediatric Surgery, Spokane, WA, USA; Corresponding author. PMG E WA Pediatric Surgery, 101 W 8th Ave, Ste 100, Spokane, WA, 99204, USA.We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child.http://www.sciencedirect.com/science/article/pii/S2213576621003249VasculitisANCACOVID-19Henoch Schonlein purpura
spellingShingle Taylor Wintler
Monica Zherebtsov
Susanne Carmack
Rebecca Muntean
Sarah J. Hill
Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
Journal of Pediatric Surgery Case Reports
Vasculitis
ANCA
COVID-19
Henoch Schonlein purpura
title Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_full Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_fullStr Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_full_unstemmed Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_short Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
title_sort acute pr3 anca vasculitis in an asymptomatic covid 19 teenager
topic Vasculitis
ANCA
COVID-19
Henoch Schonlein purpura
url http://www.sciencedirect.com/science/article/pii/S2213576621003249
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AT monicazherebtsov acutepr3ancavasculitisinanasymptomaticcovid19teenager
AT susannecarmack acutepr3ancavasculitisinanasymptomaticcovid19teenager
AT rebeccamuntean acutepr3ancavasculitisinanasymptomaticcovid19teenager
AT sarahjhill acutepr3ancavasculitisinanasymptomaticcovid19teenager