Acute and Sub-chronic Anticonvulsant Effects of Edaravone on Seizure Induced by Pentylenetetrazole or Electroshock in Mice, Nitric Oxide Involvement

Acute and Sub-chronic Anticonvulsant Effects of Edaravone on Seizure Induced by Pentylenetetrazole or Electroshock in Mice, Nitric Oxide Involvement

Background: Edaravone is an anti-stroke medication that may have nitric oxide (NO) modulating properties. This study evaluated the role of NO in the acute and sub-chronic anticonvulsant effects of edaravone in murine models of seizures induced by intraperitoneal (IP) or intravenous (IV) injections o...

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Bibliographic Details
Main Authors: Leila Moezi, Fatema Pirsalami, Mona Dastgheib, Somayeh Oftadehgan, Azar Purkhosrow, Elahe Sattarinezhad
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-05-01
Series:Iranian Journal of Medical Sciences
Subjects:
edaravone
epilepsy
pentylenetetrazole
electroshock
nitric oxide
Online Access:https://ijms.sums.ac.ir/article_49005_ad9c5a229d53263310042eb989cb4cbf.pdf

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