Acid-sensing ion channel 3 is required for agmatine-induced histamine-independent itch in mice

Acid-sensing ion channel 3 is required for agmatine-induced histamine-independent itch in mice

IntroductionItch is a common symptom of many skin and systemic diseases. Identifying novel endogenous itch mediators and the downstream signaling pathways involved will contribute to the development of new strategies for the treatment of chronic itch. In the present study, we adopted behavioral test...

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Bibliographic Details
Main Authors: Guo-Kun Zhou, Wen-Jing Xu, Yi Lu, Yan Zhou, Chen-Zhang Feng, Jiang-Tao Zhang, Shi-Yu Sun, Ruo-Meng Wang, Tong Liu, Bin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
itch
agmatine
ASIC3
atopic dermatitis
pain
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1086285/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1086285/full

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