SYSTEM OF HEMOSTASIS AND ATHEROGENESIS
Atherosclerosis concept defines the key role of inflammation in the occurrence and progression of atherosclerosis. Hemostatic system is an integral part of the inflammatory response. At all stages of atherogenesis, starting from the early stages, there is part of hemostasis factors. In recent years...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics
2016-09-01
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| Series: | Атеросклероз |
| Subjects: | |
| Online Access: | https://ateroskleroz.elpub.ru/jour/article/view/22/22 |
| _version_ | 1797963813833670656 |
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| author | A. A. Gromov M. V. Kruchinina Y. A. Schwartz V. N. Kruchinin S. V. Ryhlitsky |
| author_facet | A. A. Gromov M. V. Kruchinina Y. A. Schwartz V. N. Kruchinin S. V. Ryhlitsky |
| author_sort | A. A. Gromov |
| collection | DOAJ |
| description | Atherosclerosis concept defines the key role of inflammation in the occurrence and progression of atherosclerosis. Hemostatic system is an integral part of the inflammatory response. At all stages of atherogenesis, starting from the early stages, there is part of hemostasis factors. In recent years researchers attract most interest to the questions of intercellular interaction between platelets and leukocytes. Combined evaluation of leukocyte-platelet responses reflect the clinical and laboratory picture of atherothrombotic events in unstable angina and myocardial infarction. Monocyte-platelet interaction plays a significant role in the development of heart failure, blood platelets are capable of inducing apoptosis. The individual testing the risk of hemorrhagic complications increase the efficiency of drug prevention and therapy of antithrombotic drugs. Changing the pattern of atherosclerosis observed in recent years, also requires the introduction of new approaches in the prevention of atherosclerosis, enhancing the protection of the endothelium. This review focuses on the research, covering the role of hemostasis in the pathogenesis of atherosclerosis. |
| first_indexed | 2024-04-11T01:34:10Z |
| format | Article |
| id | doaj.art-e8922b293fe24fceae296533db5e6abc |
| institution | Directory Open Access Journal |
| issn | 2078-256X |
| language | Russian |
| last_indexed | 2024-04-11T01:34:10Z |
| publishDate | 2016-09-01 |
| publisher | Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics |
| record_format | Article |
| series | Атеросклероз |
| spelling | doaj.art-e8922b293fe24fceae296533db5e6abc2023-01-03T09:18:31ZrusSiberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and GeneticsАтеросклероз2078-256X2016-09-011233960SYSTEM OF HEMOSTASIS AND ATHEROGENESISA. A. Gromov0M. V. Kruchinina1Y. A. Schwartz2V. N. Kruchinin3S. V. Ryhlitsky4FSBSE «Scientific Research institute of therapy and preventive medicine» Russian FederationFSBSE «Scientific Research institute of therapy and preventive medicine» Russian FederationFSBSE «Scientific Research institute of therapy and preventive medicine» Russian FederationInstitute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences Russian FederationInstitute of Semiconductor Physics, Siberian Branch of the Russian Academy of Sciences Russian FederationAtherosclerosis concept defines the key role of inflammation in the occurrence and progression of atherosclerosis. Hemostatic system is an integral part of the inflammatory response. At all stages of atherogenesis, starting from the early stages, there is part of hemostasis factors. In recent years researchers attract most interest to the questions of intercellular interaction between platelets and leukocytes. Combined evaluation of leukocyte-platelet responses reflect the clinical and laboratory picture of atherothrombotic events in unstable angina and myocardial infarction. Monocyte-platelet interaction plays a significant role in the development of heart failure, blood platelets are capable of inducing apoptosis. The individual testing the risk of hemorrhagic complications increase the efficiency of drug prevention and therapy of antithrombotic drugs. Changing the pattern of atherosclerosis observed in recent years, also requires the introduction of new approaches in the prevention of atherosclerosis, enhancing the protection of the endothelium. This review focuses on the research, covering the role of hemostasis in the pathogenesis of atherosclerosis.https://ateroskleroz.elpub.ru/jour/article/view/22/22atherosclerosishemostasisplateletsatherosclerotic plaquecoagulation system |
| spellingShingle | A. A. Gromov M. V. Kruchinina Y. A. Schwartz V. N. Kruchinin S. V. Ryhlitsky SYSTEM OF HEMOSTASIS AND ATHEROGENESIS Атеросклероз atherosclerosis hemostasis platelets atherosclerotic plaque coagulation system |
| title | SYSTEM OF HEMOSTASIS AND ATHEROGENESIS |
| title_full | SYSTEM OF HEMOSTASIS AND ATHEROGENESIS |
| title_fullStr | SYSTEM OF HEMOSTASIS AND ATHEROGENESIS |
| title_full_unstemmed | SYSTEM OF HEMOSTASIS AND ATHEROGENESIS |
| title_short | SYSTEM OF HEMOSTASIS AND ATHEROGENESIS |
| title_sort | system of hemostasis and atherogenesis |
| topic | atherosclerosis hemostasis platelets atherosclerotic plaque coagulation system |
| url | https://ateroskleroz.elpub.ru/jour/article/view/22/22 |
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