Surgical management of inflammatory bowel disease in China: a systematic review of two decades
Background/AimsThe past decades have seen increasing incidence and prevalence of inflammatory bowel disease (IBD) in China. This article aimed to summarize the current status and characteristics of surgical management for IBD in China.MethodsWe searched PubMed, Embase, and Chinese databases from Jan...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Association for the Study of Intestinal Diseases
2016-10-01
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| Series: | Intestinal Research |
| Subjects: | |
| Online Access: | http://www.irjournal.org/upload/pdf/ir-14-322.pdf |
| _version_ | 1818887310204207104 |
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| author | Qiao Yu Ren Mao Lei Lian Siew chien Ng Shenghong Zhang Zhihui Chen Yanyan Zhang Yun Qiu Baili Chen Yao He Zhirong Zeng Shomron Ben-Horin Xinming Song Minhu Chen |
| author_facet | Qiao Yu Ren Mao Lei Lian Siew chien Ng Shenghong Zhang Zhihui Chen Yanyan Zhang Yun Qiu Baili Chen Yao He Zhirong Zeng Shomron Ben-Horin Xinming Song Minhu Chen |
| author_sort | Qiao Yu |
| collection | DOAJ |
| description | Background/AimsThe past decades have seen increasing incidence and prevalence of inflammatory bowel disease (IBD) in China. This article aimed to summarize the current status and characteristics of surgical management for IBD in China.MethodsWe searched PubMed, Embase, and Chinese databases from January 1, 1990 to July 1, 2014 for all relevant studies on the surgical treatment IBD in China. Eligible studies with sufficient defined variables were further reviewed for primary and secondary outcome measures.ResultsA total of 74 studies comprising 2,007 subjects with Crohn's disease (CD) and 1,085 subjects with ulcerative colitis (UC) were included. The percentage of CD patients misdiagnosed before surgery, including misdiagnosis as appendicitis or UC, was 50.8%±30.9% (578/1,268). The overall postoperative complication rate was 22.3%±13.0% (267/1,501). For studies of UC, the overall postoperative complication rate was 22.2%±27.9% (176/725). In large research centers (n>50 surgical cases), the rates of emergency operations for CD (P=0.032) and in-hospital mortalities resulting from both CD and UC were much lower than those in smaller research centers (n≤50 surgical cases) (P=0.026 and P <0.001, respectively). Regarding the changes in CD and UC surgery over time, postoperative complications (P=0.045 for CD; P=0.020 for UC) and postoperative in-hospital mortality (P=0.0002 for CD; P=0.0160 for UC) both significantly improved after the year 2010.ConclusionsThe surgical management of IBD in China has improved over time. However, the rates of misdiagnosis and postoperative complications over the past two decades have remained high. Large research centers were found to have relatively better capacity for surgical management than the smaller ones. Higher quality prospective studies are needed in China. |
| first_indexed | 2024-12-19T16:35:12Z |
| format | Article |
| id | doaj.art-e8926852f9314c1280fe5d5284bf4f22 |
| institution | Directory Open Access Journal |
| issn | 1598-9100 2288-1956 |
| language | English |
| last_indexed | 2024-12-19T16:35:12Z |
| publishDate | 2016-10-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj.art-e8926852f9314c1280fe5d5284bf4f222022-12-21T20:13:59ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562016-10-0114432233210.5217/ir.2016.14.4.322168Surgical management of inflammatory bowel disease in China: a systematic review of two decadesQiao Yu0Ren Mao1Lei Lian2Siew chien Ng3Shenghong Zhang4Zhihui Chen5Yanyan Zhang6Yun Qiu7Baili Chen8Yao He9Zhirong Zeng10Shomron Ben-Horin11Xinming Song12Minhu Chen13Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of General Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of General Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.Background/AimsThe past decades have seen increasing incidence and prevalence of inflammatory bowel disease (IBD) in China. This article aimed to summarize the current status and characteristics of surgical management for IBD in China.MethodsWe searched PubMed, Embase, and Chinese databases from January 1, 1990 to July 1, 2014 for all relevant studies on the surgical treatment IBD in China. Eligible studies with sufficient defined variables were further reviewed for primary and secondary outcome measures.ResultsA total of 74 studies comprising 2,007 subjects with Crohn's disease (CD) and 1,085 subjects with ulcerative colitis (UC) were included. The percentage of CD patients misdiagnosed before surgery, including misdiagnosis as appendicitis or UC, was 50.8%±30.9% (578/1,268). The overall postoperative complication rate was 22.3%±13.0% (267/1,501). For studies of UC, the overall postoperative complication rate was 22.2%±27.9% (176/725). In large research centers (n>50 surgical cases), the rates of emergency operations for CD (P=0.032) and in-hospital mortalities resulting from both CD and UC were much lower than those in smaller research centers (n≤50 surgical cases) (P=0.026 and P <0.001, respectively). Regarding the changes in CD and UC surgery over time, postoperative complications (P=0.045 for CD; P=0.020 for UC) and postoperative in-hospital mortality (P=0.0002 for CD; P=0.0160 for UC) both significantly improved after the year 2010.ConclusionsThe surgical management of IBD in China has improved over time. However, the rates of misdiagnosis and postoperative complications over the past two decades have remained high. Large research centers were found to have relatively better capacity for surgical management than the smaller ones. Higher quality prospective studies are needed in China.http://www.irjournal.org/upload/pdf/ir-14-322.pdfInflammatory bowel diseaseGeneral surgeryChinaSystematic review |
| spellingShingle | Qiao Yu Ren Mao Lei Lian Siew chien Ng Shenghong Zhang Zhihui Chen Yanyan Zhang Yun Qiu Baili Chen Yao He Zhirong Zeng Shomron Ben-Horin Xinming Song Minhu Chen Surgical management of inflammatory bowel disease in China: a systematic review of two decades Intestinal Research Inflammatory bowel disease General surgery China Systematic review |
| title | Surgical management of inflammatory bowel disease in China: a systematic review of two decades |
| title_full | Surgical management of inflammatory bowel disease in China: a systematic review of two decades |
| title_fullStr | Surgical management of inflammatory bowel disease in China: a systematic review of two decades |
| title_full_unstemmed | Surgical management of inflammatory bowel disease in China: a systematic review of two decades |
| title_short | Surgical management of inflammatory bowel disease in China: a systematic review of two decades |
| title_sort | surgical management of inflammatory bowel disease in china a systematic review of two decades |
| topic | Inflammatory bowel disease General surgery China Systematic review |
| url | http://www.irjournal.org/upload/pdf/ir-14-322.pdf |
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