Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review
ABO and Rh blood grouping systems are two of the non-modifiable risk factors that play an important role in the susceptibility, severity and outcomes of COVID-19 infection. This review explores these associations all over the world, in an attempt to conclude a clear idea for future reference in clin...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.1045060/full |
| _version_ | 1797955318774235136 |
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| author | Mohammad T. Abuawwad Mohammad J. J. Taha Luai Abu-Ismail Warda A. Alrubasy Shams Khalid Sameer Ibrahim T. Abuawwad Yaqeen Al-Bustanji Abdulqadir J. Nashwan |
| author_facet | Mohammad T. Abuawwad Mohammad J. J. Taha Luai Abu-Ismail Warda A. Alrubasy Shams Khalid Sameer Ibrahim T. Abuawwad Yaqeen Al-Bustanji Abdulqadir J. Nashwan |
| author_sort | Mohammad T. Abuawwad |
| collection | DOAJ |
| description | ABO and Rh blood grouping systems are two of the non-modifiable risk factors that play an important role in the susceptibility, severity and outcomes of COVID-19 infection. This review explores these associations all over the world, in an attempt to conclude a clear idea for future reference in clinical practice. In the present review, a link has been drawn between blood groups and COVID-19 transmission, course and prognosis, as literature suggests that blood group O plays a protective role against the infection, while blood group A exhibits a higher risk of exacerbation. In contrast with Rh negative individuals, Rh positive individuals are prone to more severe infection and complications, despite the fact that the underlying mechanisms of this association remain understudied. Nevertheless, the connection remains subject to controversy; since some studies report doubts about it. Thus, this association requires further investigation. |
| first_indexed | 2024-04-10T23:32:18Z |
| format | Article |
| id | doaj.art-e892d632e2ed46d0a84f81e2bc5946a9 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-10T23:32:18Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-e892d632e2ed46d0a84f81e2bc5946a92023-01-12T06:11:21ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-01-01910.3389/fmed.2022.10450601045060Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A reviewMohammad T. Abuawwad0Mohammad J. J. Taha1Luai Abu-Ismail2Warda A. Alrubasy3Shams Khalid Sameer4Ibrahim T. Abuawwad5Yaqeen Al-Bustanji6Abdulqadir J. Nashwan7Department of Clinical Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptDepartment of Clinical Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptDepartment of Ophthalmology, Islamic Hospital, Amman, JordanDepartment of Clinical Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptDepartment of Clinical Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptDepartment of Clinical Medicine, Faculty of Medicine, Cairo University, Cairo, EgyptDepartment of Clinical Medical, School of Medicine, University of Jordan, Amman, JordanDepartment of Nursing, Hamad Medical Corporation, Doha, QatarABO and Rh blood grouping systems are two of the non-modifiable risk factors that play an important role in the susceptibility, severity and outcomes of COVID-19 infection. This review explores these associations all over the world, in an attempt to conclude a clear idea for future reference in clinical practice. In the present review, a link has been drawn between blood groups and COVID-19 transmission, course and prognosis, as literature suggests that blood group O plays a protective role against the infection, while blood group A exhibits a higher risk of exacerbation. In contrast with Rh negative individuals, Rh positive individuals are prone to more severe infection and complications, despite the fact that the underlying mechanisms of this association remain understudied. Nevertheless, the connection remains subject to controversy; since some studies report doubts about it. Thus, this association requires further investigation.https://www.frontiersin.org/articles/10.3389/fmed.2022.1045060/fullABO blood groupsCOVID-19hematologyRH factorSARS-CoV-2 |
| spellingShingle | Mohammad T. Abuawwad Mohammad J. J. Taha Luai Abu-Ismail Warda A. Alrubasy Shams Khalid Sameer Ibrahim T. Abuawwad Yaqeen Al-Bustanji Abdulqadir J. Nashwan Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review Frontiers in Medicine ABO blood groups COVID-19 hematology RH factor SARS-CoV-2 |
| title | Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review |
| title_full | Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review |
| title_fullStr | Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review |
| title_full_unstemmed | Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review |
| title_short | Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review |
| title_sort | effects of abo blood groups and rh factor on covid 19 transmission course and outcome a review |
| topic | ABO blood groups COVID-19 hematology RH factor SARS-CoV-2 |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.1045060/full |
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