Mechanistic insights of ABC importer HutCD involved in heme internalization by Vibrio cholerae

Abstract Heme internalization by pathogenic bacteria inside a human host to accomplish the requirement of iron for important cellular processes is of paramount importance. Despite this, the mechanism of heme import by the ATP-binding-cassette (ABC) transporter HutCD in Vibrio cholerae remains unexpl...

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Bibliographic Details
Main Authors: Indrila Saha, Shrestha Chakraborty, Shubhangi Agarwal, Peeali Mukherjee, Biplab Ghosh, Jhimli Dasgupta
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11213-9