Thrombotic Events Are Unusual Toxicities of Chimeric Antigen Receptor T-Cell Therapies

Thrombotic Events Are Unusual Toxicities of Chimeric Antigen Receptor T-Cell Therapies

Chimeric antigen receptor (CAR) T-cell therapy has greatly transformed the treatment and prognosis of B-cell hematological malignancies. As CAR T-cell therapy continues to be more readily adopted and indications increase, the field’s recognition of emerging toxicities will continue to grow. Among th...

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Bibliographic Details
Main Authors: Christopher Schorr, Jorge Forindez, Manuel Espinoza-Gutarra, Rakesh Mehta, Natalie Grover, Fabiana Perna
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
chimeric antigen receptor (CAR) T-cell
thrombotic events
cytokine release syndrome (CRS)
immune effector cell-associated neurotoxicity syndrome (ICANS)
hematological malignancies
disseminated intravascular coagulation (DIC)
Online Access:https://www.mdpi.com/1422-0067/24/9/8349

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https://www.mdpi.com/1422-0067/24/9/8349

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