Prolonged Disease-Free Survival in a Relapsed Adult Granulosa Cell Tumor of the Ovary Treated by Combined Leuprolide and Letrozole: Case Report

Prolonged Disease-Free Survival in a Relapsed Adult Granulosa Cell Tumor of the Ovary Treated by Combined Leuprolide and Letrozole: Case Report

Relapsing ovarian granulosa-cell tumor (GCT) is a challenge for physicians due to the lack of effective therapy. Current strategies did not improve the 80% death rate of recurrent disease. GCTs synthesize estrogens and express follicle-stimulating hormone, gonadotropin-releasing hormone, and estroge...

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Bibliographic Details
Main Authors: Giancarlo Garuti, Paola Francesca Sagrada, Susanna Delfrati, Lorenzo Sogaro, Marco Soligo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Reproductive Medicine
Subjects:
granulosa-cell tumor
ovary
ovarian cancer
GnRH agonists
aromatase inhibitors
FOXL-2
Online Access:https://www.mdpi.com/2673-3897/3/4/23

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