Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility
Two turmeric food powders (C1 and C2) were studied for curcuminoid content and their effects on the guinea pig intestinal tract in vitro. C1 contained a higher curcuminoid content than C2 (5.22% vs 2.31%). C1 and C2 increased gallbladder (∼10%) and biliary smooth muscle tone (∼15%), without affectin...
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-12-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S175646462200384X |
| _version_ | 1828275570495979520 |
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| author | Matteo Micucci Roberta Budriesi Mara Mandrioli Matilde Tura Ivan Corazza Maria Frosini Rita Aldini Laura Beatrice Mattioli Tullia Gallina Toschi |
| author_facet | Matteo Micucci Roberta Budriesi Mara Mandrioli Matilde Tura Ivan Corazza Maria Frosini Rita Aldini Laura Beatrice Mattioli Tullia Gallina Toschi |
| author_sort | Matteo Micucci |
| collection | DOAJ |
| description | Two turmeric food powders (C1 and C2) were studied for curcuminoid content and their effects on the guinea pig intestinal tract in vitro. C1 contained a higher curcuminoid content than C2 (5.22% vs 2.31%). C1 and C2 increased gallbladder (∼10%) and biliary smooth muscle tone (∼15%), without affecting the sphincter of Oddi smooth muscle contractility. C2 was more effective than C1 in lowering ileum tone (–22% vs −37%), whereas the reverse occurred in the colon (-50% vs −20%). Standard Fast Fourier transforms and absolute powers analysis of the frequency bands highlighted that, in the bile duct, C2 induced contractions of higher variability and ampler oscillations of low-frequency waves. At the Oddi sphincter, C1 had a biphasic effect, increasing and then drastically decreasing the oscillations. The same occurred with C2 in the ileum, while both samples reduced the fluctuations in the colon. |
| first_indexed | 2024-04-13T06:48:52Z |
| format | Article |
| id | doaj.art-e89dd9a5c5794c8e97f3bbc15a15d0d1 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-04-13T06:48:52Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-e89dd9a5c5794c8e97f3bbc15a15d0d12022-12-22T02:57:28ZengElsevierJournal of Functional Foods1756-46462022-12-0199105314Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractilityMatteo Micucci0Roberta Budriesi1Mara Mandrioli2Matilde Tura3Ivan Corazza4Maria Frosini5Rita Aldini6Laura Beatrice Mattioli7Tullia Gallina Toschi8Department of Biomolecular Sciences, Università degli Studi di Urbino “Carlo Bo”, 61029 Urbino, Italy; UniCamillus - Saint Camillus International University of Health Sciences, Rome, ItalyDepartment of Pharmacy and Biotechnology, Food Chemistry and Nutraceutical Lab, Alma Mater Studiorum-University of Bologna, 40126 Bologna, ItalyDepartment of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, Viale Fanin 40, 40127 Bologna, ItalyDepartment of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, Viale Fanin 40, 40127 Bologna, Italy; Corresponding author at: Department of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, Viale Fanin 40, 40127 Bologna, Italy.Department of Specialistic, Experimental and Diagnostic Medicine, Alma Mater Studiorum-University of Bologna, S. Orsola Hospital, 40126 Bologna, ItalyDepartment of Life Sciences, University of Siena, 53100 Siena, ItalyDepartment of Pharmacy and Biotechnology, Food Chemistry and Nutraceutical Lab, Alma Mater Studiorum-University of Bologna, 40126 Bologna, ItalyDepartment of Pharmacy and Biotechnology, Food Chemistry and Nutraceutical Lab, Alma Mater Studiorum-University of Bologna, 40126 Bologna, ItalyDepartment of Agricultural and Food Sciences, Alma Mater Studiorum-University of Bologna, Viale Fanin 40, 40127 Bologna, ItalyTwo turmeric food powders (C1 and C2) were studied for curcuminoid content and their effects on the guinea pig intestinal tract in vitro. C1 contained a higher curcuminoid content than C2 (5.22% vs 2.31%). C1 and C2 increased gallbladder (∼10%) and biliary smooth muscle tone (∼15%), without affecting the sphincter of Oddi smooth muscle contractility. C2 was more effective than C1 in lowering ileum tone (–22% vs −37%), whereas the reverse occurred in the colon (-50% vs −20%). Standard Fast Fourier transforms and absolute powers analysis of the frequency bands highlighted that, in the bile duct, C2 induced contractions of higher variability and ampler oscillations of low-frequency waves. At the Oddi sphincter, C1 had a biphasic effect, increasing and then drastically decreasing the oscillations. The same occurred with C2 in the ileum, while both samples reduced the fluctuations in the colon.http://www.sciencedirect.com/science/article/pii/S175646462200384XCurcuma spiceIleumProximal colonBiliary tractGallbladder |
| spellingShingle | Matteo Micucci Roberta Budriesi Mara Mandrioli Matilde Tura Ivan Corazza Maria Frosini Rita Aldini Laura Beatrice Mattioli Tullia Gallina Toschi Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility Journal of Functional Foods Curcuma spice Ileum Proximal colon Biliary tract Gallbladder |
| title | Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility |
| title_full | Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility |
| title_fullStr | Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility |
| title_full_unstemmed | Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility |
| title_short | Effects of turmeric powder on intestinal and biliary functions: The influence of curcuminoids concentration on spontaneous contractility |
| title_sort | effects of turmeric powder on intestinal and biliary functions the influence of curcuminoids concentration on spontaneous contractility |
| topic | Curcuma spice Ileum Proximal colon Biliary tract Gallbladder |
| url | http://www.sciencedirect.com/science/article/pii/S175646462200384X |
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