Targeting Farnesoid X receptor (FXR) for developing novel therapeutics against cancer

Targeting Farnesoid X receptor (FXR) for developing novel therapeutics against cancer

Abstract Cancer is one of the lethal diseases that arise due to the molecular alterations in the cell. One of those alterations associated with cancer corresponds to differential expression of Farnesoid X receptor (FXR), a nuclear receptor regulating bile, cholesterol homeostasis, lipid, and glucose...

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Bibliographic Details
Main Authors: Sosmitha Girisa, Sahu Henamayee, Dey Parama, Varsha Rana, Uma Dutta, Ajaikumar B. Kunnumakkara
Format: Article
Language:English
Published: Springer 2021-07-01
Series:Molecular Biomedicine
Subjects:
Cancer
FXR
Cell signalling
Agonist
Antagonist
Online Access:https://doi.org/10.1186/s43556-021-00035-2

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