Bergapten Improves Scopolamine-Induced Memory Impairment in Mice via Cholinergic and Antioxidative Mechanisms

Bergapten Improves Scopolamine-Induced Memory Impairment in Mice via Cholinergic and Antioxidative Mechanisms

Bergapten is a furanocoumarin naturally occurring in the Apiaceae family and it is a well-known photosensitizing agent used in photochemotherapy. In this study, we investigated the influence of bergapten on cognitive function and mechanism underlying these effects in scopolamine-induced memory impai...

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Bibliographic Details
Main Authors: Joanna Kowalczyk, Łukasz Kurach, Anna Boguszewska-Czubara, Krystyna Skalicka-Woźniak, Marta Kruk-Słomka, Jacek Kurzepa, Małgorzata Wydrzynska-Kuźma, Grażyna Biała, Adrianna Skiba, Barbara Budzyńska
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neuroscience
Subjects:
acetylcholine
oxidative stress
coumarins
memory
passive avoidance
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00730/full

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