Polymorphisms in DNA Repair and Xenobiotic Biotransformation Enzyme Genes and Lung Cancer Risk in Coal Mine Workers

Polymorphisms in DNA Repair and Xenobiotic Biotransformation Enzyme Genes and Lung Cancer Risk in Coal Mine Workers

Background: Currently coal mining employs over 7 million miners globally. This occupational setting is associated with exposure to dust particles, heavy metals, polycyclic aromatic hydrocarbons and radioactive radon, significantly increasing the risk of lung cancer (LC). The susceptibility for LC is...

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Bibliographic Details
Main Authors: Varvara Minina, Anna Timofeeva, Anastasya Torgunakova, Olga Soboleva, Marina Bakanova, Yana Savchenko, Elena Voronina, Andrey Glushkov, Alexander Prosekov, Aleksandra Fucic
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Life
Subjects:
lung cancer: miner
genetic polymorphism
<i>GSTM1</i> (deletion)
<i>APEX1</i>
<i>XPD</i>
<i>NBS1</i>
Online Access:https://www.mdpi.com/2075-1729/12/2/255

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