Vitamin D and Calcium Supplementation Accelerate Vascular Calcification in a Model of Pseudoxanthoma Elasticum

Vitamin D and Calcium Supplementation Accelerate Vascular Calcification in a Model of Pseudoxanthoma Elasticum

Arterial calcification is a common feature of pseudoxanthoma elasticum (PXE), a disease characterized by <i>ABCC6</i> mutations, inducing a deficiency in pyrophosphate, a key inhibitor of calcium phosphate crystallization in arteries. Methods: we analyzed whether long-term exposure of Ab...

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Bibliographic Details
Main Authors: Elise Bouderlique, Ellie Tang, Jeremy Zaworski, Amélie Coudert, Dominique Bazin, Ferenc Borondics, Jean-Philippe Haymann, Georges Leftheriotis, Ludovic Martin, Michel Daudon, Emmanuel Letavernier
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin D
calcium
calcification
vascular
pseudoxanthoma elasticum
pyrophosphate
Online Access:https://www.mdpi.com/1422-0067/23/4/2302

Internet

https://www.mdpi.com/1422-0067/23/4/2302

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