Phenotypic Adaptation of <i>Pseudomonas aeruginosa</i> in the Presence of Siderophore-Antibiotic Conjugates during Epithelial Cell Infection

Phenotypic Adaptation of <i>Pseudomonas aeruginosa</i> in the Presence of Siderophore-Antibiotic Conjugates during Epithelial Cell Infection

Iron acquisition pathways have often been considered to be gateways for the uptake of antibiotics into bacteria. Bacteria excrete chelators, called siderophores, to access iron. Antibiotic molecules can be covalently attached to siderophores for their transport into pathogens during the iron-uptake...

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Bibliographic Details
Main Authors: Quentin Perraud, Paola Cantero, Mathilde Munier, Françoise Hoegy, Nicolas Zill, Véronique Gasser, Gaëtan L. A. Mislin, Laurence Ehret-Sabatier, Isabelle J. Schalk
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Microorganisms
Subjects:
siderophore
siderophore–antibiotic
<i>Pseudomonas aeruginosa</i>
TonB dependent transporters
iron uptake
proteomic
Online Access:https://www.mdpi.com/2076-2607/8/11/1820

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