Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy

Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy

Abstract We report a 54‐year‐old man with treatment‐resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

Bibliographic Details
Main Authors: Ziyan S. Ahmed, Rinsha P. V. Sherin, Tatiana L. Fonseca, Thanh D. Hoang, Mohamed K. M. Shakir
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Clinical Case Reports
Subjects:
depression
hypothyroidism
polymorphism
T3
Online Access:https://doi.org/10.1002/ccr3.5651

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