Update on trabecular bone score
ABSTRACT Trabecular bone score (TBS) is an indirect and noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density (BMD). There is substantial evidence suppor...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Brazilian Society of Endocrinology and Metabolism
2022-12-01
|
| Series: | Archives of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000500694&tlng=en |
| _version_ | 1811179278247657472 |
|---|---|
| author | Telma Palomo Patricia Muszkat Fernanda G. Weiler Patricia Dreyer Cynthia M. A. Brandão Barbara C. Silva |
| author_facet | Telma Palomo Patricia Muszkat Fernanda G. Weiler Patricia Dreyer Cynthia M. A. Brandão Barbara C. Silva |
| author_sort | Telma Palomo |
| collection | DOAJ |
| description | ABSTRACT Trabecular bone score (TBS) is an indirect and noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density (BMD). There is substantial evidence supporting the use of TBS to assess vertebral, hip, and major osteoporotic fracture risk in postmenopausal women, as well as to assess hip and major osteoporotic fracture risk in men aged > 50 years. TBS complements BMD information and can be used to adjust the FRAX (Fracture Risk Assessment) score to improve risk stratification. While TBS should not be used to monitor antiresorptive therapy, it may be potentially useful for monitoring anabolic therapy. There is also a growing body of evidence indicating that TBS is particularly useful as an adjunct to BMD for fracture risk assessment in conditions associated with increased fracture risk, such as type-2 diabetes, chronic corticosteroid excess, and other conditions wherein BMD readings are often misleading. The interference of abdominal soft tissue thickness (STT) on TBS should also be considered when interpreting these findings because image noise can impact TBS evaluation. A new TBS software version based on an algorithm that accounts for STT rather than BMI seems to correct this technical limitation and is under development. In this paper, we review the current state of TBS, its technical aspects, and its evolving role in the assessment and management of several clinical conditions. |
| first_indexed | 2024-04-11T06:33:13Z |
| format | Article |
| id | doaj.art-e8aa74e7e25a43128531d4f28c6c7da0 |
| institution | Directory Open Access Journal |
| issn | 2359-4292 |
| language | English |
| last_indexed | 2024-04-11T06:33:13Z |
| publishDate | 2022-12-01 |
| publisher | Brazilian Society of Endocrinology and Metabolism |
| record_format | Article |
| series | Archives of Endocrinology and Metabolism |
| spelling | doaj.art-e8aa74e7e25a43128531d4f28c6c7da02022-12-22T04:39:59ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-42922022-12-0166569470610.20945/2359-3997000000559Update on trabecular bone scoreTelma Palomohttps://orcid.org/0000-0002-1655-7319Patricia Muszkathttps://orcid.org/0000-0002-7727-2392Fernanda G. Weilerhttps://orcid.org/0000-0002-8000-3919Patricia Dreyerhttps://orcid.org/0000-0002-3710-0043Cynthia M. A. Brandãohttps://orcid.org/0000-0001-5382-567XBarbara C. Silvahttps://orcid.org/0000-0001-7276-581XABSTRACT Trabecular bone score (TBS) is an indirect and noninvasive measure of bone quality. A low TBS indicates degraded bone microarchitecture, predicts osteoporotic fracture, and is partially independent of clinical risk factors and bone mineral density (BMD). There is substantial evidence supporting the use of TBS to assess vertebral, hip, and major osteoporotic fracture risk in postmenopausal women, as well as to assess hip and major osteoporotic fracture risk in men aged > 50 years. TBS complements BMD information and can be used to adjust the FRAX (Fracture Risk Assessment) score to improve risk stratification. While TBS should not be used to monitor antiresorptive therapy, it may be potentially useful for monitoring anabolic therapy. There is also a growing body of evidence indicating that TBS is particularly useful as an adjunct to BMD for fracture risk assessment in conditions associated with increased fracture risk, such as type-2 diabetes, chronic corticosteroid excess, and other conditions wherein BMD readings are often misleading. The interference of abdominal soft tissue thickness (STT) on TBS should also be considered when interpreting these findings because image noise can impact TBS evaluation. A new TBS software version based on an algorithm that accounts for STT rather than BMI seems to correct this technical limitation and is under development. In this paper, we review the current state of TBS, its technical aspects, and its evolving role in the assessment and management of several clinical conditions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000500694&tlng=enTrabecular bone scoredual-energy X-ray absorptiometryosteoporosisfracture risksecondary osteoporosis |
| spellingShingle | Telma Palomo Patricia Muszkat Fernanda G. Weiler Patricia Dreyer Cynthia M. A. Brandão Barbara C. Silva Update on trabecular bone score Archives of Endocrinology and Metabolism Trabecular bone score dual-energy X-ray absorptiometry osteoporosis fracture risk secondary osteoporosis |
| title | Update on trabecular bone score |
| title_full | Update on trabecular bone score |
| title_fullStr | Update on trabecular bone score |
| title_full_unstemmed | Update on trabecular bone score |
| title_short | Update on trabecular bone score |
| title_sort | update on trabecular bone score |
| topic | Trabecular bone score dual-energy X-ray absorptiometry osteoporosis fracture risk secondary osteoporosis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972022000500694&tlng=en |
| work_keys_str_mv | AT telmapalomo updateontrabecularbonescore AT patriciamuszkat updateontrabecularbonescore AT fernandagweiler updateontrabecularbonescore AT patriciadreyer updateontrabecularbonescore AT cynthiamabrandao updateontrabecularbonescore AT barbaracsilva updateontrabecularbonescore |