Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma

Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma

Background: Cutaneous squamous cell carcinomas (cSCC) are among the most common and highly mutated human malignancies. Understanding the impact of DNA methylation in cSCC may provide avenues for new therapeutic strategies. Methods: We used reduced-representation bisulfite sequencing for DNA methylat...

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Bibliographic Details
Main Authors:	Kevin Roth, Louis Coussement, Elena V. Knatko, Maureen Higgins, Sandra Steyaert, Charlotte M. Proby, Tim de Meyer, Albena T. Dinkova-Kostova
Format:	Article
Language:	English
Published:	Elsevier 2021-05-01
Series:	EBioMedicine
Subjects:	cSCC DNA methylation RRBS FILIP1L
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396421001766

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