Deep brain stimulation of the Cuneiform nucleus for levodopa-resistant freezing of gait in Parkinson’s disease: study protocol for a prospective, pilot trial

Deep brain stimulation of the Cuneiform nucleus for levodopa-resistant freezing of gait in Parkinson’s disease: study protocol for a prospective, pilot trial

Abstract Background Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset of Parkinson’s disease (PD) patients that is poorly responsive to standard levodopa therapy or deep brain stimulation (DBS) of established PD targets such as the subthalamic nucleus and the globu...

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Bibliographic Details
Main Authors: Stephano J. Chang, Iahn Cajigas, James D. Guest, Brian R. Noga, Eva Widerström-Noga, Ihtsham Haq, Letitia Fisher, Corneliu C. Luca, Jonathan R. Jagid
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Pilot and Feasibility Studies
Subjects:
Freezing of gait (FOG)
Gait dysfunction
Parkinson’s disease
Mesencephalic locomotor region (MLR)
Cuneiform nucleus (CnF)
Pedunculopontine nucleus (PPN)
Online Access:https://doi.org/10.1186/s40814-021-00855-7

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