The Potential Equivalents of <i>TET2</i> Mutations

The Potential Equivalents of <i>TET2</i> Mutations

TET2 is a dioxygenase dependent on Fe<sup>2+</sup> and α-ketoglutarate which oxidizes 5-methylcytosine (5meC) to 5-hydroxymethylcytosine (5hmeC). TET proteins successively oxidize 5mC to yield 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Among th...

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Bibliographic Details
Main Authors: Sergiu Pasca, Ancuta Jurj, Mihnea Zdrenghea, Ciprian Tomuleasa
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
TET2
mutations
equivalent
expression
Online Access:https://www.mdpi.com/2072-6694/13/7/1499

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