The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study
Background: Renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. The aim of this study was to determine the final outcome of renal involvement in leptospirosis. Methods: This longitudinal prospective study included...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Babol University of Medical Sciences
2016-01-01
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| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/browse.php?a_code=A-10-302-1&slc_lang=en&sid=1 |
| _version_ | 1818537879647813632 |
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| author | Roya Ghasemian Mehran Shokri Atieh Makhlough Mohammad amin Suraki-Azad |
| author_facet | Roya Ghasemian Mehran Shokri Atieh Makhlough Mohammad amin Suraki-Azad |
| author_sort | Roya Ghasemian |
| collection | DOAJ |
| description | Background: Renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. The aim of this study was to determine the final outcome of renal involvement in leptospirosis.
Methods: This longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. All patients were followed for three months while all patients with renal failure were followed-up for one year.
Results: Fifty-one patients, 53.5±14.8 years (82.4% males) with acute renal failure were studied. Over the hospitalization period, 28 patients recovered, and seven (13.72%) patients died of multiple organ failure. At the time of discharge, 16 patients had mild renal failure. Over the follow-up period, all patients recovered but in two patients renal failure persisted at creatinine level of 1.5 mg/dl.
Conclusion: Development of renal failure in leptospirosis is not rare. Recovery of renal function may last several months. However, most patients recover completely at least after one year. |
| first_indexed | 2024-12-11T18:56:26Z |
| format | Article |
| id | doaj.art-e8b75b35957744eb917827d1282357ca |
| institution | Directory Open Access Journal |
| issn | 2008-6164 2008-6172 |
| language | English |
| last_indexed | 2024-12-11T18:56:26Z |
| publishDate | 2016-01-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj.art-e8b75b35957744eb917827d1282357ca2022-12-22T00:54:08ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722016-01-0171712The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up studyRoya Ghasemian0Mehran Shokri1Atieh Makhlough2Mohammad amin Suraki-Azad3 Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences,Sari,Iran. Infectious Diseases and Tropical Medicine Research Center, Babol University of Medical Science, Babol, Iran. Mazandaran University of Medical Science, Sari ,Iran. Mazandaran University of Medical Science, Sari ,Iran. Background: Renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. The aim of this study was to determine the final outcome of renal involvement in leptospirosis. Methods: This longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. All patients were followed for three months while all patients with renal failure were followed-up for one year. Results: Fifty-one patients, 53.5±14.8 years (82.4% males) with acute renal failure were studied. Over the hospitalization period, 28 patients recovered, and seven (13.72%) patients died of multiple organ failure. At the time of discharge, 16 patients had mild renal failure. Over the follow-up period, all patients recovered but in two patients renal failure persisted at creatinine level of 1.5 mg/dl. Conclusion: Development of renal failure in leptospirosis is not rare. Recovery of renal function may last several months. However, most patients recover completely at least after one year.http://caspjim.com/browse.php?a_code=A-10-302-1&slc_lang=en&sid=1acute renal failure chronic renal failure hepatic dysfunction leptospirosis multiple organ failure |
| spellingShingle | Roya Ghasemian Mehran Shokri Atieh Makhlough Mohammad amin Suraki-Azad The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study Caspian Journal of Internal Medicine acute renal failure chronic renal failure hepatic dysfunction leptospirosis multiple organ failure |
| title | The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study |
| title_full | The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study |
| title_fullStr | The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study |
| title_full_unstemmed | The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study |
| title_short | The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study |
| title_sort | course and outcome of renal failure due to human leptospirosis referred to a hospital in north of iran a follow up study |
| topic | acute renal failure chronic renal failure hepatic dysfunction leptospirosis multiple organ failure |
| url | http://caspjim.com/browse.php?a_code=A-10-302-1&slc_lang=en&sid=1 |
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