Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer

In recent years, squamous non-small cell lung cancer (NSCLC) didn’t progress much in chemotherapy or target therapy. However, immunotherapy has made breakthroughs in treating squamous NSCLC. Immunotherapy includes two main broad classes of immune checkpoint inhibitors and therapeutic vaccines. Immun...

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Main Authors: Shouzheng WANG, Junling LI
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2016-10-01
Series:Chinese Journal of Lung Cancer
Subjects:
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2016.10.09
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author Shouzheng WANG
Junling LI
author_facet Shouzheng WANG
Junling LI
author_sort Shouzheng WANG
collection DOAJ
description In recent years, squamous non-small cell lung cancer (NSCLC) didn’t progress much in chemotherapy or target therapy. However, immunotherapy has made breakthroughs in treating squamous NSCLC. Immunotherapy includes two main broad classes of immune checkpoint inhibitors and therapeutic vaccines. Immune checkpoint inhibitors, including anti cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) and anti programmed death receptor 1 (PD-1) antibodies, have been tested in the phase II/III clinical trials and have demonstrated promising outcomes. Immunotherapy will become an important treatment for squamous NSCLC.
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spelling doaj.art-e8c6f15140804e81ab497e22ad8964022022-12-21T23:04:29ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872016-10-011910pagepage10.3779/j.issn.1009-3419.2016.10.09Progress in Immunotherapy for Squamous Non-small Cell Lung CancerShouzheng WANG0Junling LI1National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 
Beijing 100021, ChinaNational Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 
Beijing 100021, ChinaIn recent years, squamous non-small cell lung cancer (NSCLC) didn’t progress much in chemotherapy or target therapy. However, immunotherapy has made breakthroughs in treating squamous NSCLC. Immunotherapy includes two main broad classes of immune checkpoint inhibitors and therapeutic vaccines. Immune checkpoint inhibitors, including anti cytotoxic T-lymphocyte associated antigen 4 (CTLA-4) and anti programmed death receptor 1 (PD-1) antibodies, have been tested in the phase II/III clinical trials and have demonstrated promising outcomes. Immunotherapy will become an important treatment for squamous NSCLC.http://dx.doi.org/10.3779/j.issn.1009-3419.2016.10.09Lung neoplasmsImmunotherapyCheckpoint inhibitorsTumour vaccines
spellingShingle Shouzheng WANG
Junling LI
Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer
Lung neoplasms
Immunotherapy
Checkpoint inhibitors
Tumour vaccines
title Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer
title_full Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer
title_fullStr Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer
title_full_unstemmed Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer
title_short Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer
title_sort progress in immunotherapy for squamous non small cell lung cancer
topic Lung neoplasms
Immunotherapy
Checkpoint inhibitors
Tumour vaccines
url http://dx.doi.org/10.3779/j.issn.1009-3419.2016.10.09
work_keys_str_mv AT shouzhengwang progressinimmunotherapyforsquamousnonsmallcelllungcancer
AT junlingli progressinimmunotherapyforsquamousnonsmallcelllungcancer