Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility.
Leukocyte immunoglobulin-like receptor A3 (LILRA3) is a soluble immune regulatory molecule primarily expressed by monocytes and macrophages. A homozygous 6.7kbp LILRA3 gene deletion that removes the first seven of its eight exons is predicted to lead to lack of LILRA3 protein, although this has not...
Main Authors: | Hongyan An, Chai Lim, Gilles J Guillemin, Ute Vollmer-Conna, William Rawlinson, Katherine Bryant, Nicodemus Tedla |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4752247?pdf=render |
Similar Items
-
LP-093 Role of leukocyte immunoglobulin-like receptor a3 (LILRA3) in the pathogenesis of lupus-like disease
by: Chen Chen, et al.
Published: (2023-07-01) -
LP-087 LILRA3 plays a protective role in MAS-like disease
by: Chen Chen, et al.
Published: (2023-07-01) -
Fibrinogen induces inflammatory responses via the immune activating receptor LILRA2
by: Yifan Li, et al.
Published: (2024-09-01) -
PB2158: EXPLORING THE BIOLOGICAL ROLE OF LILRA4 IN MANTLE CELL LYMPHOMA
by: M. K. Blum, et al.
Published: (2022-06-01) -
Correction: LILRA2 Selectively Modulates LPS-Mediated Cytokine Production and Inhibits Phagocytosis by Monocytes
Published: (2012-01-01)