Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review
Immunotherapy has been shown to be highly effective in some types of cancer caused by viruses. Gene therapy involves insertion or modification of a therapeutic gene, to correct for inappropriate gene products that cause/may cause diseases. Both these types of therapy have been used as alternative wa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/13/5/822 |
| _version_ | 1827693523363692544 |
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| author | Nathália Alves Araújo de Almeida Camilla Rodrigues de Almeida Ribeiro Jéssica Vasques Raposo Vanessa Salete de Paula |
| author_facet | Nathália Alves Araújo de Almeida Camilla Rodrigues de Almeida Ribeiro Jéssica Vasques Raposo Vanessa Salete de Paula |
| author_sort | Nathália Alves Araújo de Almeida |
| collection | DOAJ |
| description | Immunotherapy has been shown to be highly effective in some types of cancer caused by viruses. Gene therapy involves insertion or modification of a therapeutic gene, to correct for inappropriate gene products that cause/may cause diseases. Both these types of therapy have been used as alternative ways to avoid cancers caused by oncoviruses. In this review, we summarize recent studies on immunotherapy and gene therapy including the topics of oncolytic immunotherapy, immune checkpoint inhibitors, gene replacement, antisense oligonucleotides, RNA interference, clustered regularly interspaced short palindromic repeats Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-based gene editing, transcription activator-like effector nucleases (TALENs) and custom treatment for Epstein–Barr virus, human T-lymphotropic virus 1, hepatitis B virus, human papillomavirus, hepatitis C virus, herpesvirus associated with Kaposi’s sarcoma, Merkel cell polyomavirus, and cytomegalovirus. |
| first_indexed | 2024-03-10T11:45:45Z |
| format | Article |
| id | doaj.art-e8ce94192be743408af7e1917776c8e2 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T11:45:45Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-e8ce94192be743408af7e1917776c8e22023-11-21T18:10:47ZengMDPI AGViruses1999-49152021-05-0113582210.3390/v13050822Immunotherapy and Gene Therapy for Oncoviruses Infections: A ReviewNathália Alves Araújo de Almeida0Camilla Rodrigues de Almeida Ribeiro1Jéssica Vasques Raposo2Vanessa Salete de Paula3Laboratory of Molecular Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, 21040-360 Rio de Janeiro, BrazilLaboratory of Molecular Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, 21040-360 Rio de Janeiro, BrazilLaboratory of Molecular Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, 21040-360 Rio de Janeiro, BrazilLaboratory of Molecular Virology, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, 21040-360 Rio de Janeiro, BrazilImmunotherapy has been shown to be highly effective in some types of cancer caused by viruses. Gene therapy involves insertion or modification of a therapeutic gene, to correct for inappropriate gene products that cause/may cause diseases. Both these types of therapy have been used as alternative ways to avoid cancers caused by oncoviruses. In this review, we summarize recent studies on immunotherapy and gene therapy including the topics of oncolytic immunotherapy, immune checkpoint inhibitors, gene replacement, antisense oligonucleotides, RNA interference, clustered regularly interspaced short palindromic repeats Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-based gene editing, transcription activator-like effector nucleases (TALENs) and custom treatment for Epstein–Barr virus, human T-lymphotropic virus 1, hepatitis B virus, human papillomavirus, hepatitis C virus, herpesvirus associated with Kaposi’s sarcoma, Merkel cell polyomavirus, and cytomegalovirus.https://www.mdpi.com/1999-4915/13/5/822immunotherapygene therapy and oncovirus |
| spellingShingle | Nathália Alves Araújo de Almeida Camilla Rodrigues de Almeida Ribeiro Jéssica Vasques Raposo Vanessa Salete de Paula Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review Viruses immunotherapy gene therapy and oncovirus |
| title | Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review |
| title_full | Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review |
| title_fullStr | Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review |
| title_full_unstemmed | Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review |
| title_short | Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review |
| title_sort | immunotherapy and gene therapy for oncoviruses infections a review |
| topic | immunotherapy gene therapy and oncovirus |
| url | https://www.mdpi.com/1999-4915/13/5/822 |
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