Ischemic Sciatic Neuropathy in a Patient with Liposarcoma

Background Various etiologies are the causative agents for sciatic neuropathy. We present here a case of ischemic sciatic neuropathy in a patient with liposarcoma. Case report A 55-year-old woman presented with severe pain and weakness of the left leg. She had a history of recurred retroperitoneal l...

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Main Authors: Jieun Lee, Jun Hong Lee, Gyu Sik Kim, Min Cheol Park, Naeun Woo, Jeong Hee Cho
Format: Article
Language:English
Published: The Korean Neurocritical Care Society 2017-06-01
Series:Journal of Neurocritical Care
Subjects:
Online Access:http://www.e-jnc.org/upload/pdf/jnc-160100.pdf
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author Jieun Lee
Jun Hong Lee
Gyu Sik Kim
Min Cheol Park
Naeun Woo
Jeong Hee Cho
author_facet Jieun Lee
Jun Hong Lee
Gyu Sik Kim
Min Cheol Park
Naeun Woo
Jeong Hee Cho
author_sort Jieun Lee
collection DOAJ
description Background Various etiologies are the causative agents for sciatic neuropathy. We present here a case of ischemic sciatic neuropathy in a patient with liposarcoma. Case report A 55-year-old woman presented with severe pain and weakness of the left leg. She had a history of recurred retroperitoneal liposarcoma, and was being administered chemotherapy. Examination revealed weakness in ankle dorsiflexion, plantar flexion and hamstring. Complaints also included dysesthesia, and numbness in the sole and dorsum of the foot. Nerve conduction study showed low compound muscle action potentials and slow motor conduction velocity of left peroneal and tibial nerves, with indiscernible sensory nerve action potentials of the left superficial peroneal and sural nerves. Computed tomography angiography revealed occlusion of the left common iliac artery. Commencement of intravenous infusion of heparin resulted in skin color change and progression of the weakness. Hence, the patient underwent an emergency thrombectomy. Conclusions Ischemia should be considered as a cause of sciatic neuropathy in cancer patients, which requires management with timely treatment.
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spelling doaj.art-e8ceacb368ff4146830d55be80e086142022-12-21T18:48:12ZengThe Korean Neurocritical Care SocietyJournal of Neurocritical Care2005-03482508-13492017-06-01101283110.18700/jnc.160100253Ischemic Sciatic Neuropathy in a Patient with LiposarcomaJieun Lee0Jun Hong Lee1Gyu Sik Kim2Min Cheol Park3Naeun Woo4Jeong Hee Cho5Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, KoreaDepartment of Neurology, National Health Insurance Service Ilsan Hospital, Goyang, KoreaBackground Various etiologies are the causative agents for sciatic neuropathy. We present here a case of ischemic sciatic neuropathy in a patient with liposarcoma. Case report A 55-year-old woman presented with severe pain and weakness of the left leg. She had a history of recurred retroperitoneal liposarcoma, and was being administered chemotherapy. Examination revealed weakness in ankle dorsiflexion, plantar flexion and hamstring. Complaints also included dysesthesia, and numbness in the sole and dorsum of the foot. Nerve conduction study showed low compound muscle action potentials and slow motor conduction velocity of left peroneal and tibial nerves, with indiscernible sensory nerve action potentials of the left superficial peroneal and sural nerves. Computed tomography angiography revealed occlusion of the left common iliac artery. Commencement of intravenous infusion of heparin resulted in skin color change and progression of the weakness. Hence, the patient underwent an emergency thrombectomy. Conclusions Ischemia should be considered as a cause of sciatic neuropathy in cancer patients, which requires management with timely treatment.http://www.e-jnc.org/upload/pdf/jnc-160100.pdfSciatic neuropathyLiposarcomaIschemia
spellingShingle Jieun Lee
Jun Hong Lee
Gyu Sik Kim
Min Cheol Park
Naeun Woo
Jeong Hee Cho
Ischemic Sciatic Neuropathy in a Patient with Liposarcoma
Journal of Neurocritical Care
Sciatic neuropathy
Liposarcoma
Ischemia
title Ischemic Sciatic Neuropathy in a Patient with Liposarcoma
title_full Ischemic Sciatic Neuropathy in a Patient with Liposarcoma
title_fullStr Ischemic Sciatic Neuropathy in a Patient with Liposarcoma
title_full_unstemmed Ischemic Sciatic Neuropathy in a Patient with Liposarcoma
title_short Ischemic Sciatic Neuropathy in a Patient with Liposarcoma
title_sort ischemic sciatic neuropathy in a patient with liposarcoma
topic Sciatic neuropathy
Liposarcoma
Ischemia
url http://www.e-jnc.org/upload/pdf/jnc-160100.pdf
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