Dimethyl 2-(1-Methyl-3-oxo-1,3-dihydroisobenzofuran-1-yl)malonate

Dimethyl 2-(1-Methyl-3-oxo-1,3-dihydroisobenzofuran-1-yl)malonate

In this work we report a facile access to a 3,3-disubstituted isobenzofuranone by tandem addition/cyclization reaction to methyl 2-acetylbenzoate in the presence of dimethyl malonate, under basic conditions.

Bibliographic Details
Main Authors:	Antonia Di Mola, Rosanna Filosa, Antonio Massa
Format:	Article
Language:	English
Published:	MDPI AG 2020-04-01
Series:	Molbank
Subjects:	phthalide isobenzofuranone quaternary carbon cascade reactions
Online Access:	https://www.mdpi.com/1422-8599/2020/2/M1124

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