A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia
Background: Erythema nodosum leprosum (ENL) has a chronic and recurrent nature which could reduce patient’s quality of life in addition to the onset of ENL that occurs before, during, or after multidrug treatment, further emphasizing the importance of regular control and education.Purpose:This study...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Indonesian |
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Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga
2021-03-01
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| Series: | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
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| Online Access: | https://e-journal.unair.ac.id/BIKK/article/view/22658 |
| _version_ | 1797506065433100288 |
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| author | Cindy Fransisca Iskandar Zulkarnain Evy Ervianti Damayanti Damayanti Maylita Sari Budiono Budiono Medhi Denisa Alinda Bagus Haryo Kusumaputra Muhammad Yulianto Listiawan |
| author_facet | Cindy Fransisca Iskandar Zulkarnain Evy Ervianti Damayanti Damayanti Maylita Sari Budiono Budiono Medhi Denisa Alinda Bagus Haryo Kusumaputra Muhammad Yulianto Listiawan |
| author_sort | Cindy Fransisca |
| collection | DOAJ |
| description | Background: Erythema nodosum leprosum (ENL) has a chronic and recurrent nature which could reduce patient’s quality of life in addition to the onset of ENL that occurs before, during, or after multidrug treatment, further emphasizing the importance of regular control and education.Purpose:This study aimed to evaluate the epidemiology, onset, duration, and recurrence of ENL. Methods:Data from medical records were obtained for a 3-year retrospective study of multibacillary leprosy patients at the Leprosy Division of the Dermatology and Venereology Outpatient Department, Dr. Soetomo General Hospital Surabaya, with a minimum of 2–5 years follow-up period.Result:The prevalence of ENL continued to increase almost every year especially in 2017 (32% in 2015; 32% in 2016; and 36% in 2017). ENL most often occurs during the first year of multi-drug therapy (MDT) administration followed by after the release from treatment (RFT) with the latest onset occurring 4 years after RFT. The majority of patients experienced chronic and recurrent reactions with the longest reactions lasting up to 4.5 years (55 months). Conclusion:Knowledge about the onset, duration, and recurrences of ENL are essential, and strict supervision for routine control shall be encouraged to increase the patients’ compliance so as to increase their quality of life. |
| first_indexed | 2024-03-10T04:27:17Z |
| format | Article |
| id | doaj.art-e8d06a2cef1043329bf958909d27b7f3 |
| institution | Directory Open Access Journal |
| issn | 1978-4279 2549-4082 |
| language | Indonesian |
| last_indexed | 2024-03-10T04:27:17Z |
| publishDate | 2021-03-01 |
| publisher | Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga |
| record_format | Article |
| series | Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) |
| spelling | doaj.art-e8d06a2cef1043329bf958909d27b7f32023-11-23T06:33:58ZindDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas AirlanggaBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)1978-42792549-40822021-03-0133181210.20473/bikk.V33.1.2021.8-1218544A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, IndonesiaCindy Fransisca0Iskandar Zulkarnain1Evy Ervianti2Damayanti Damayanti3Maylita Sari4Budiono Budiono5Medhi Denisa Alinda6Bagus Haryo Kusumaputra7Muhammad Yulianto Listiawan8Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Public Health Sciences, Faculty of Medicine, Universitas Airlangga, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Teaching Hospital, SurabayaBackground: Erythema nodosum leprosum (ENL) has a chronic and recurrent nature which could reduce patient’s quality of life in addition to the onset of ENL that occurs before, during, or after multidrug treatment, further emphasizing the importance of regular control and education.Purpose:This study aimed to evaluate the epidemiology, onset, duration, and recurrence of ENL. Methods:Data from medical records were obtained for a 3-year retrospective study of multibacillary leprosy patients at the Leprosy Division of the Dermatology and Venereology Outpatient Department, Dr. Soetomo General Hospital Surabaya, with a minimum of 2–5 years follow-up period.Result:The prevalence of ENL continued to increase almost every year especially in 2017 (32% in 2015; 32% in 2016; and 36% in 2017). ENL most often occurs during the first year of multi-drug therapy (MDT) administration followed by after the release from treatment (RFT) with the latest onset occurring 4 years after RFT. The majority of patients experienced chronic and recurrent reactions with the longest reactions lasting up to 4.5 years (55 months). Conclusion:Knowledge about the onset, duration, and recurrences of ENL are essential, and strict supervision for routine control shall be encouraged to increase the patients’ compliance so as to increase their quality of life.https://e-journal.unair.ac.id/BIKK/article/view/22658erythema nodosum leprosumepidemiologyonsetdurationrecurrent |
| spellingShingle | Cindy Fransisca Iskandar Zulkarnain Evy Ervianti Damayanti Damayanti Maylita Sari Budiono Budiono Medhi Denisa Alinda Bagus Haryo Kusumaputra Muhammad Yulianto Listiawan A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology) erythema nodosum leprosum epidemiology onset duration recurrent |
| title | A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia |
| title_full | A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia |
| title_fullStr | A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia |
| title_full_unstemmed | A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia |
| title_short | A Retrospective Study: Epidemiology, Onset, and Duration of Erythema Nodosum Leprosum in Surabaya, Indonesia |
| title_sort | retrospective study epidemiology onset and duration of erythema nodosum leprosum in surabaya indonesia |
| topic | erythema nodosum leprosum epidemiology onset duration recurrent |
| url | https://e-journal.unair.ac.id/BIKK/article/view/22658 |
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