Cardiogenic shock induced by a high dose of intravenous morphine
Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects. It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nofer Institute of Occupational Medicine
2021-01-01
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| Series: | International Journal of Occupational Medicine and Environmental Health |
| Subjects: | |
| Online Access: | http://ijomeh.eu/Cardiogenic-shock-induced-by-a-high-dose-of-intravenous-morphine,128068,0,2.html |
| Summary: | Morphine is an opiate alkaloid characterized by various clinical effects, among which the most prominent are its analgesic and psychoactive effects.
It also has a prominent depressive effect on the respiratory and cardiovascular system. Because of its psychoactive effect, morphine is very addictive
and often used as a recreational narcotic. As a medication, it has found its use as an analgesic agent in chronic pain treatment, in hemorrhagic shock,
and in acute heart failure with pulmonary edema. Albeit, morphine use in heart failure is controversial, based on many observational studies showing
the negative effect on the outcomes of the patients treated with morphine during acute cardiovascular incidents. In this report, the authors present
a case of cardiogenic shock (CS) with transient left ventricular ejection fraction reduction, occurring in a patient attempting suicide using a high dose
of intravenous morphine sulphate administration. Other CS causes were ruled out. To the best of the authors’ knowledge, this is the second case of
a morphine-related CS reported in literature. Int J Occup Med Environ Health. 2021;34(1):133–8 |
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| ISSN: | 1232-1087 1896-494X |