Hepatic Osteodystrophy: The Mechanism of Bone Loss in Hepatocellular Disease and the Effects of Pamidronate Treatment

OBJECTIVES: The present study was designed to evaluate the bone phenotypes and mechanisms involved in bone disorders associated with hepatic osteodystrophy. Hepatocellular disease was induced by carbon tetrachloride (CCl4). In addition, the effects of disodium pamidronate on bone tissue were evaluat...

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Bibliographic Details
Main Authors: Adriano L. Spirlandeli, Ingrid Dick-de-Paula, Ariane Zamarioli, Vanda Jorgetti, Leandra N.Z. Ramalho, Marcello H. Nogueira-Barbosa, Jose B. Volpon, Alceu A. Jordão, Fernando Q. Cunha, Sandra Y. Fukada, Francisco J.A. de Paula
Format: Article
Language:English
Published: Elsevier España
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322017000400231&lng=en&tlng=en