Sample size planning in the design and analysis of cluster randomized trials using the symbolic two-step method

Introduction: Evidence that can be used to improve clinical practice patterns and processes is frequently generated through standard, parallel-arms cluster randomized trial (CRT) designs that test interventions implemented at the center-level. Although the primary endpoint of these trials is often a...

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Bibliographic Details
Main Authors: David Zahrieh, Jennifer Le-Rademacher
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Contemporary Clinical Trials Communications
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865420300934