Physical aspects of biological activity and cancer
Mitochondria are organelles at the boundary between chemical–genetic and physical processes in living cells. Mitochondria supply energy and provide conditions for physical mechanisms. Protons transferred across the inner mitochondrial membrane diffuse into cytosol and form a zone of a strong static...
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| Format: | Article |
| Language: | English |
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AIP Publishing LLC
2012-03-01
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| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/1.3699057 |
| _version_ | 1818928566152200192 |
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| author | Jiří Pokorný |
| author_facet | Jiří Pokorný |
| author_sort | Jiří Pokorný |
| collection | DOAJ |
| description | Mitochondria are organelles at the boundary between chemical–genetic and physical processes in living cells. Mitochondria supply energy and provide conditions for physical mechanisms. Protons transferred across the inner mitochondrial membrane diffuse into cytosol and form a zone of a strong static electric field changing water into quasi-elastic medium that loses viscosity damping properties. Mitochondria and microtubules form a unique cooperating system in the cell. Microtubules are electrical polar structures that make possible non-linear transformation of random excitations into coherent oscillations and generation of coherent electrodynamic field. Mitochondria supply energy, may condition non-linear properties and low damping of oscillations. Electrodynamic activity might have essential significance for material transport, organization, intra- and inter-cellular interactions, and information transfer. Physical processes in cancer cell are disturbed due to suppression of oxidative metabolism in mitochodria (Warburg effect). Water ordering level in the cell is decreased, excitation of microtubule electric polar oscilations diminished, damping increased, and non-linear energy transformation shifted towards the linear region. Power and coherence of the generated electrodynamic field are reduced. Electromagnetic activity of healthy and cancer cells may display essential differences. Local invasion and metastastatic growth may strongly depend on disturbed electrodynamic activity. Nanotechnological measurements may disclose yet unknown properties and parameters of electrodynamic oscillations and other physical processes in healthy and cancer cells. |
| first_indexed | 2024-12-20T03:30:56Z |
| format | Article |
| id | doaj.art-e8d5fe938bc04cb48d2e254f5434c925 |
| institution | Directory Open Access Journal |
| issn | 2158-3226 |
| language | English |
| last_indexed | 2024-12-20T03:30:56Z |
| publishDate | 2012-03-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | AIP Advances |
| spelling | doaj.art-e8d5fe938bc04cb48d2e254f5434c9252022-12-21T19:55:00ZengAIP Publishing LLCAIP Advances2158-32262012-03-0121011207011207-1110.1063/1.3699057100201ADVPhysical aspects of biological activity and cancerJiří Pokorný0Institute of Photonics and Electronics AS CR, Chaberská 57, Prague 8, Czech RepublicMitochondria are organelles at the boundary between chemical–genetic and physical processes in living cells. Mitochondria supply energy and provide conditions for physical mechanisms. Protons transferred across the inner mitochondrial membrane diffuse into cytosol and form a zone of a strong static electric field changing water into quasi-elastic medium that loses viscosity damping properties. Mitochondria and microtubules form a unique cooperating system in the cell. Microtubules are electrical polar structures that make possible non-linear transformation of random excitations into coherent oscillations and generation of coherent electrodynamic field. Mitochondria supply energy, may condition non-linear properties and low damping of oscillations. Electrodynamic activity might have essential significance for material transport, organization, intra- and inter-cellular interactions, and information transfer. Physical processes in cancer cell are disturbed due to suppression of oxidative metabolism in mitochodria (Warburg effect). Water ordering level in the cell is decreased, excitation of microtubule electric polar oscilations diminished, damping increased, and non-linear energy transformation shifted towards the linear region. Power and coherence of the generated electrodynamic field are reduced. Electromagnetic activity of healthy and cancer cells may display essential differences. Local invasion and metastastatic growth may strongly depend on disturbed electrodynamic activity. Nanotechnological measurements may disclose yet unknown properties and parameters of electrodynamic oscillations and other physical processes in healthy and cancer cells.http://dx.doi.org/10.1063/1.3699057 |
| spellingShingle | Jiří Pokorný Physical aspects of biological activity and cancer AIP Advances |
| title | Physical aspects of biological activity and cancer |
| title_full | Physical aspects of biological activity and cancer |
| title_fullStr | Physical aspects of biological activity and cancer |
| title_full_unstemmed | Physical aspects of biological activity and cancer |
| title_short | Physical aspects of biological activity and cancer |
| title_sort | physical aspects of biological activity and cancer |
| url | http://dx.doi.org/10.1063/1.3699057 |
| work_keys_str_mv | AT jiripokorny physicalaspectsofbiologicalactivityandcancer |