Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan)
The efficacy and safety of intravenous topotecan (hycamtin) given in a dose of 4 mg/m2 on days of 1, 8, 15 of a 28-day cycle of its therapy were evaluated in patients with recurrent ovarian cancer (OC).Preliminary analysis of the safety and toxicity of the topotecan regimen demonstrated no impact on...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2014-07-01
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| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/152 |
| _version_ | 1797876112005529600 |
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| author | E. G. Novikova I. A. Korneyeva E. Yu. Moskovskaya |
| author_facet | E. G. Novikova I. A. Korneyeva E. Yu. Moskovskaya |
| author_sort | E. G. Novikova |
| collection | DOAJ |
| description | The efficacy and safety of intravenous topotecan (hycamtin) given in a dose of 4 mg/m2 on days of 1, 8, 15 of a 28-day cycle of its therapy were evaluated in patients with recurrent ovarian cancer (OC).Preliminary analysis of the safety and toxicity of the topotecan regimen demonstrated no impact on quality of life, easiness-to-use, and possible outpatient use. Topotecan showed to be effective as second- and higher line therapy for recurrent OC to carry out a platinum reduction. |
| first_indexed | 2024-04-10T01:58:06Z |
| format | Article |
| id | doaj.art-e8d8c871cf9240d6addb9829754265b0 |
| institution | Directory Open Access Journal |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| last_indexed | 2024-04-10T01:58:06Z |
| publishDate | 2014-07-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj.art-e8d8c871cf9240d6addb9829754265b02023-03-13T08:44:32ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-010111311810.17650/1994-4098-2011-0-1-113-118168Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan)E. G. Novikova0I. A. Korneyeva1E. Yu. Moskovskaya2Отделение гинекологии ФГУ МНИОИ им. П.А. Герцена Минздравсоцразвития РФОтделение гинекологии ФГУ МНИОИ им. П.А. Герцена Минздравсоцразвития РФОтделение гинекологии ФГУ МНИОИ им. П.А. Герцена Минздравсоцразвития РФThe efficacy and safety of intravenous topotecan (hycamtin) given in a dose of 4 mg/m2 on days of 1, 8, 15 of a 28-day cycle of its therapy were evaluated in patients with recurrent ovarian cancer (OC).Preliminary analysis of the safety and toxicity of the topotecan regimen demonstrated no impact on quality of life, easiness-to-use, and possible outpatient use. Topotecan showed to be effective as second- and higher line therapy for recurrent OC to carry out a platinum reduction.https://ojrs.abvpress.ru/ojrs/article/view/152диссеминированный рак яичниковбезрецидивный интервалбесплатиновый интервалтопотекан |
| spellingShingle | E. G. Novikova I. A. Korneyeva E. Yu. Moskovskaya Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan) Опухоли женской репродуктивной системы диссеминированный рак яичников безрецидивный интервал бесплатиновый интервал топотекан |
| title | Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan) |
| title_full | Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan) |
| title_fullStr | Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan) |
| title_full_unstemmed | Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan) |
| title_short | Recurrent ovarian cancer: prolongation of the platinum-free interval with the use of a weekly treatment regimen of hycamtin (topotecan) |
| title_sort | recurrent ovarian cancer prolongation of the platinum free interval with the use of a weekly treatment regimen of hycamtin topotecan |
| topic | диссеминированный рак яичников безрецидивный интервал бесплатиновый интервал топотекан |
| url | https://ojrs.abvpress.ru/ojrs/article/view/152 |
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