Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals

Engineered noble metal nanomaterials (NMN) possess adjustable optical, electrical, and biocompatible properties that make them excellent tools for probing the nano‐bio‐interface. Understanding their interactions with biomolecules, cells, and tissues at the nano‐bio‐interface is crucial in designing...

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Main Authors: Peng Guo, Yiyun Wang, Hongbo Cui, Xiang Yao, Guijian Guan, Ming‐Yong Han
Format: Article
Language:English
Published: Wiley-VCH 2024-04-01
Series:Small Science
Subjects:
Online Access:https://doi.org/10.1002/smsc.202300227
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author Peng Guo
Yiyun Wang
Hongbo Cui
Xiang Yao
Guijian Guan
Ming‐Yong Han
author_facet Peng Guo
Yiyun Wang
Hongbo Cui
Xiang Yao
Guijian Guan
Ming‐Yong Han
author_sort Peng Guo
collection DOAJ
description Engineered noble metal nanomaterials (NMN) possess adjustable optical, electrical, and biocompatible properties that make them excellent tools for probing the nano‐bio‐interface. Understanding their interactions with biomolecules, cells, and tissues at the nano‐bio‐interface is crucial in designing these nanomaterials for biomedical applications. This review summarizes the structure, properties, synthesis, and passivation methods of noble metal nanoparticles, as well as the construction strategy and detection technology of the nano‐bio‐interface to provide important information about their uptake, distribution, metabolism, and degradation in vivo and in vitro. The related action mechanisms include the kinetic and thermodynamic processes of the nano‐bio‐interface, the driving forces for its formation, and the chemical reactions at the nano‐bio‐interface. By exploring the action mechanism of the nano‐bio‐interface, the antibacterial properties and cytotoxicity of NMN could be better understood, and open up more extensive biological applications. Finally, the future trends of NMNs in the biological field and the challenges encountered in realizing these technologies are discussed.
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spelling doaj.art-e8d8ea18a6e34f3d9c1b9d5cb80df8582024-04-16T04:15:54ZengWiley-VCHSmall Science2688-40462024-04-0144n/an/a10.1002/smsc.202300227Nano‐bio‐interface: Unleashing the Potential of Noble NanometalsPeng Guo0Yiyun Wang1Hongbo Cui2Xiang Yao3Guijian Guan4Ming‐Yong Han5Institute of Molecular Plus Tianjin University 92 Weijin Road Tianjin 300072 ChinaInstitute of Molecular Plus Tianjin University 92 Weijin Road Tianjin 300072 ChinaInstitute of Molecular Plus Tianjin University 92 Weijin Road Tianjin 300072 ChinaInstitute of Molecular Plus Tianjin University 92 Weijin Road Tianjin 300072 ChinaInstitute of Molecular Plus Tianjin University 92 Weijin Road Tianjin 300072 ChinaInstitute of Molecular Plus Tianjin University 92 Weijin Road Tianjin 300072 ChinaEngineered noble metal nanomaterials (NMN) possess adjustable optical, electrical, and biocompatible properties that make them excellent tools for probing the nano‐bio‐interface. Understanding their interactions with biomolecules, cells, and tissues at the nano‐bio‐interface is crucial in designing these nanomaterials for biomedical applications. This review summarizes the structure, properties, synthesis, and passivation methods of noble metal nanoparticles, as well as the construction strategy and detection technology of the nano‐bio‐interface to provide important information about their uptake, distribution, metabolism, and degradation in vivo and in vitro. The related action mechanisms include the kinetic and thermodynamic processes of the nano‐bio‐interface, the driving forces for its formation, and the chemical reactions at the nano‐bio‐interface. By exploring the action mechanism of the nano‐bio‐interface, the antibacterial properties and cytotoxicity of NMN could be better understood, and open up more extensive biological applications. Finally, the future trends of NMNs in the biological field and the challenges encountered in realizing these technologies are discussed.https://doi.org/10.1002/smsc.202300227bioapplicationsfunctionalitynano‐bio‐interfacenoble nanomaterials
spellingShingle Peng Guo
Yiyun Wang
Hongbo Cui
Xiang Yao
Guijian Guan
Ming‐Yong Han
Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals
Small Science
bioapplications
functionality
nano‐bio‐interface
noble nanomaterials
title Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals
title_full Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals
title_fullStr Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals
title_full_unstemmed Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals
title_short Nano‐bio‐interface: Unleashing the Potential of Noble Nanometals
title_sort nano bio interface unleashing the potential of noble nanometals
topic bioapplications
functionality
nano‐bio‐interface
noble nanomaterials
url https://doi.org/10.1002/smsc.202300227
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AT yiyunwang nanobiointerfaceunleashingthepotentialofnoblenanometals
AT hongbocui nanobiointerfaceunleashingthepotentialofnoblenanometals
AT xiangyao nanobiointerfaceunleashingthepotentialofnoblenanometals
AT guijianguan nanobiointerfaceunleashingthepotentialofnoblenanometals
AT mingyonghan nanobiointerfaceunleashingthepotentialofnoblenanometals