Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal infection.

Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal infection.

Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. A number of group A streptococcus vaccine candidates have been developed, but only one 26-valent recombinant M p...

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Bibliographic Details
Main Authors: Chih-Feng Kuo, Nina Tsao, I-Chen Hsieh, Yee-Shin Lin, Jiunn-Jong Wu, Yu-Ting Hung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5371370?pdf=render

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