Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift
Background: In addition to heart disease, ECG also changes in non-heart disease, which due to its similarity, can lead to misdiagnosis of heart disease in patients. ECG changes in brain lesions such as ischemic and hemorrhagic strokes, brain traumas, etc. and have been studied in many articles, but...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2022-10-01
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| Series: | Tehran University Medical Journal |
| Subjects: | |
| Online Access: | http://tumj.tums.ac.ir/article-1-11962-en.html |
| _version_ | 1811189168548610048 |
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| author | Majid Zamani Masoudeh Babakhanian Farhad Heydari Mohammad Nasr-Esfahani Mohammad Mahdi Zarezadeh |
| author_facet | Majid Zamani Masoudeh Babakhanian Farhad Heydari Mohammad Nasr-Esfahani Mohammad Mahdi Zarezadeh |
| author_sort | Majid Zamani |
| collection | DOAJ |
| description | Background: In addition to heart disease, ECG also changes in non-heart disease, which due to its similarity, can lead to misdiagnosis of heart disease in patients. ECG changes in brain lesions such as ischemic and hemorrhagic strokes, brain traumas, etc. and have been studied in many articles, but the effects of brain midline shift on ECG changes have not been studied. In this study, we want to examine these changes.
Methods: This is a prospective cross-sectional descriptive study. Patients with brain tumors who were referred to Al-Zahra and Kashani hospitals in Isfahan from April 2019 to March 2021 were selected. Patients with a history of heart disease, patients receiving medications that cause ECG changes, patients with ECG changes due to non-cardiac and cerebral causes, and individuals under 15 years of age were not included in the study. Patients whose ECG changes were due to electrolyte disturbances or acute heart problems were also excluded from the study. After obtaining informed consent from patients, a CT scan or brain MRI was taken and patients were divided into two groups with and without midline shift. Then the ECG was taken and ECG changes (T wave, ST segment, QTc Interval, QRS prolongation) were compared in two groups of brain tumors with and without midline shift.
Results: 136 patients were included in the study. Of these, 69 patients were in the without midline shift group and 67 patients were in the midline shift group. In the midline shift group, 3% of patients had ST segment changes and 23.9% had T wave changes, which were 1.4% and 10.1% in the without midline shift group, respectively. The mean QTc Interval in the two groups without and with midline shift was 338.26 (4 28.438) and 388.66 (37.855), respectively, and the mean QRS in the without midline shift group was 86.09 (88.9.88) ms and in the midline shift group was 94.63 (±12.83) ms.
Conclusion: Brain midline shifts can cause QRS widening, QTc interval prolongation, and T-wave changes in patients' ECGs. |
| first_indexed | 2024-04-11T14:31:26Z |
| format | Article |
| id | doaj.art-e8dd46b38bd047b2a4406a5cf1191e29 |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-04-11T14:31:26Z |
| publishDate | 2022-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-e8dd46b38bd047b2a4406a5cf1191e292022-12-22T04:18:38ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222022-10-01807539545Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shiftMajid Zamani0Masoudeh Babakhanian1Farhad Heydari2Mohammad Nasr-Esfahani3Mohammad Mahdi Zarezadeh4 Department of Emergency Medicine, School of Medicine, Isfahan University of Medicine, Isfahan, Iran. Abnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran. Department of Emergency Medicine, School of Medicine, Isfahan University of Medicine, Isfahan, Iran. Department of Emergency Medicine, School of Medicine, Isfahan University of Medicine, Isfahan, Iran. Department of Emergency Medicine, School of Medicine, Isfahan University of Medicine, Isfahan, Iran. Background: In addition to heart disease, ECG also changes in non-heart disease, which due to its similarity, can lead to misdiagnosis of heart disease in patients. ECG changes in brain lesions such as ischemic and hemorrhagic strokes, brain traumas, etc. and have been studied in many articles, but the effects of brain midline shift on ECG changes have not been studied. In this study, we want to examine these changes. Methods: This is a prospective cross-sectional descriptive study. Patients with brain tumors who were referred to Al-Zahra and Kashani hospitals in Isfahan from April 2019 to March 2021 were selected. Patients with a history of heart disease, patients receiving medications that cause ECG changes, patients with ECG changes due to non-cardiac and cerebral causes, and individuals under 15 years of age were not included in the study. Patients whose ECG changes were due to electrolyte disturbances or acute heart problems were also excluded from the study. After obtaining informed consent from patients, a CT scan or brain MRI was taken and patients were divided into two groups with and without midline shift. Then the ECG was taken and ECG changes (T wave, ST segment, QTc Interval, QRS prolongation) were compared in two groups of brain tumors with and without midline shift. Results: 136 patients were included in the study. Of these, 69 patients were in the without midline shift group and 67 patients were in the midline shift group. In the midline shift group, 3% of patients had ST segment changes and 23.9% had T wave changes, which were 1.4% and 10.1% in the without midline shift group, respectively. The mean QTc Interval in the two groups without and with midline shift was 338.26 (4 28.438) and 388.66 (37.855), respectively, and the mean QRS in the without midline shift group was 86.09 (88.9.88) ms and in the midline shift group was 94.63 (±12.83) ms. Conclusion: Brain midline shifts can cause QRS widening, QTc interval prolongation, and T-wave changes in patients' ECGs.http://tumj.tums.ac.ir/article-1-11962-en.htmlbrain neoplasmselectrocardiographymidline shift. |
| spellingShingle | Majid Zamani Masoudeh Babakhanian Farhad Heydari Mohammad Nasr-Esfahani Mohammad Mahdi Zarezadeh Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift Tehran University Medical Journal brain neoplasms electrocardiography midline shift. |
| title | Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift |
| title_full | Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift |
| title_fullStr | Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift |
| title_full_unstemmed | Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift |
| title_short | Comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift |
| title_sort | comparative study of electrocardiogram changes in patients with brain tumors with midline shift and without midline shift |
| topic | brain neoplasms electrocardiography midline shift. |
| url | http://tumj.tums.ac.ir/article-1-11962-en.html |
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