Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved]
Background: With evolving techniques for analysis of blood pressure (BP) variability, the importance of sampling resolution for intra-operative BP still remains to be examined. This study aims at comparing BP data with beat-by-beat vs. 15 second resolution. Methods: This is a retrospective analysis...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2018-03-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/7-275/v1 |
| _version_ | 1818913493227667456 |
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| author | Senthil Packiasabapathy Ammu T. Susheela Fernando Mujica Balachundhar Subramaniam |
| author_facet | Senthil Packiasabapathy Ammu T. Susheela Fernando Mujica Balachundhar Subramaniam |
| author_sort | Senthil Packiasabapathy |
| collection | DOAJ |
| description | Background: With evolving techniques for analysis of blood pressure (BP) variability, the importance of sampling resolution for intra-operative BP still remains to be examined. This study aims at comparing BP data with beat-by-beat vs. 15 second resolution. Methods: This is a retrospective analysis of intra-arterial BP data obtained from cardiac surgical patients from the intra-operative period. Data was collected from two sources for each patient, one with beat-by-beat frequency, other at a frequency of once every 15 seconds. The fraction of time and area under the curve beyond systolic BP thresholds of 95 – 135 mmHg were calculated using data from both sources, for each patient. These were compared using Wilcoxon ranked sum test for paired samples using R-statistics version 3.4.3. Results: There was a statistically significant difference (P < 0.001) between the parameters from the two sources. This was especially true for parameters below and outside the thresholds. Only time fraction showed significant difference above the 135 mmHg threshold. Conclusion: Our preliminary analysis shows a definitive difference between BP descriptors, depending on sampling resolution. But the impact of this difference on the outcome predicting models of the parameters stands to be ascertained. Future larger studies, powered to examine the impact of sampling resolution on outcome predictive ability of BP descriptors, with special emphasis on dynamic markers of complexity are warranted. |
| first_indexed | 2024-12-19T23:31:22Z |
| format | Article |
| id | doaj.art-e8ddb11d379b408cbb080d3ba405ed54 |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-19T23:31:22Z |
| publishDate | 2018-03-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-e8ddb11d379b408cbb080d3ba405ed542022-12-21T20:01:43ZengF1000 Research LtdF1000Research2046-14022018-03-01710.12688/f1000research.13810.115012Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved]Senthil Packiasabapathy0Ammu T. Susheela1Fernando Mujica2Balachundhar Subramaniam3Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USADepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USADepartment of Anesthesia, University of Kansas Medical Center, School of Medicine, University of Kansas, Kansas City, KS, 66160, USADepartment of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USABackground: With evolving techniques for analysis of blood pressure (BP) variability, the importance of sampling resolution for intra-operative BP still remains to be examined. This study aims at comparing BP data with beat-by-beat vs. 15 second resolution. Methods: This is a retrospective analysis of intra-arterial BP data obtained from cardiac surgical patients from the intra-operative period. Data was collected from two sources for each patient, one with beat-by-beat frequency, other at a frequency of once every 15 seconds. The fraction of time and area under the curve beyond systolic BP thresholds of 95 – 135 mmHg were calculated using data from both sources, for each patient. These were compared using Wilcoxon ranked sum test for paired samples using R-statistics version 3.4.3. Results: There was a statistically significant difference (P < 0.001) between the parameters from the two sources. This was especially true for parameters below and outside the thresholds. Only time fraction showed significant difference above the 135 mmHg threshold. Conclusion: Our preliminary analysis shows a definitive difference between BP descriptors, depending on sampling resolution. But the impact of this difference on the outcome predicting models of the parameters stands to be ascertained. Future larger studies, powered to examine the impact of sampling resolution on outcome predictive ability of BP descriptors, with special emphasis on dynamic markers of complexity are warranted.https://f1000research.com/articles/7-275/v1 |
| spellingShingle | Senthil Packiasabapathy Ammu T. Susheela Fernando Mujica Balachundhar Subramaniam Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved] F1000Research |
| title | Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved] |
| title_full | Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved] |
| title_fullStr | Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved] |
| title_full_unstemmed | Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved] |
| title_short | Significance of intra-operative blood pressure data resolution: A retrospective, observational study [version 1; referees: 2 approved] |
| title_sort | significance of intra operative blood pressure data resolution a retrospective observational study version 1 referees 2 approved |
| url | https://f1000research.com/articles/7-275/v1 |
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