Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects
The repair and reconstruction of bone defects and the inhibition of local tumor recurrence are two common problems in bone surgery. The rapid development of biomedicine, clinical medicine, and material science has promoted the research and development of synthetic degradable polymer anti-tumor bone...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1096525/full |
| _version_ | 1797905083653947392 |
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| author | Honghao Yu Honghao Yu Haifeng Liu Yuan Shen Qiang Ao Qiang Ao |
| author_facet | Honghao Yu Honghao Yu Haifeng Liu Yuan Shen Qiang Ao Qiang Ao |
| author_sort | Honghao Yu |
| collection | DOAJ |
| description | The repair and reconstruction of bone defects and the inhibition of local tumor recurrence are two common problems in bone surgery. The rapid development of biomedicine, clinical medicine, and material science has promoted the research and development of synthetic degradable polymer anti-tumor bone repair materials. Compared with natural polymer materials, synthetic polymer materials have machinable mechanical properties, highly controllable degradation properties, and uniform structure, which has attracted more attention from researchers. In addition, adopting new technologies is an effective strategy for developing new bone repair materials. The application of nanotechnology, 3D printing technology, and genetic engineering technology is beneficial to modify the performance of materials. Photothermal therapy, magnetothermal therapy, and anti-tumor drug delivery may provide new directions for the research and development of anti-tumor bone repair materials. This review focuses on recent advances in synthetic biodegradable polymer bone repair materials and their antitumor properties. |
| first_indexed | 2024-04-10T09:59:25Z |
| format | Article |
| id | doaj.art-e8e4c141323e492090f9edd8d8427f11 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-10T09:59:25Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-e8e4c141323e492090f9edd8d8427f112023-02-16T11:01:44ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852023-02-011110.3389/fbioe.2023.10965251096525Synthetic biodegradable polymer materials in the repair of tumor-associated bone defectsHonghao Yu0Honghao Yu1Haifeng Liu2Yuan Shen3Qiang Ao4Qiang Ao5Departments of Spine Surgery, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Tissue Engineering, China Medical University, Shenyang, ChinaDepartments of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartments of Spine Surgery, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Tissue Engineering, China Medical University, Shenyang, ChinaNMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial and Institute of Regulatory Science for Medical Device and National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, ChinaThe repair and reconstruction of bone defects and the inhibition of local tumor recurrence are two common problems in bone surgery. The rapid development of biomedicine, clinical medicine, and material science has promoted the research and development of synthetic degradable polymer anti-tumor bone repair materials. Compared with natural polymer materials, synthetic polymer materials have machinable mechanical properties, highly controllable degradation properties, and uniform structure, which has attracted more attention from researchers. In addition, adopting new technologies is an effective strategy for developing new bone repair materials. The application of nanotechnology, 3D printing technology, and genetic engineering technology is beneficial to modify the performance of materials. Photothermal therapy, magnetothermal therapy, and anti-tumor drug delivery may provide new directions for the research and development of anti-tumor bone repair materials. This review focuses on recent advances in synthetic biodegradable polymer bone repair materials and their antitumor properties.https://www.frontiersin.org/articles/10.3389/fbioe.2023.1096525/fullsyntheticdegradablepolymer materialsbone defectrepair |
| spellingShingle | Honghao Yu Honghao Yu Haifeng Liu Yuan Shen Qiang Ao Qiang Ao Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects Frontiers in Bioengineering and Biotechnology synthetic degradable polymer materials bone defect repair |
| title | Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects |
| title_full | Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects |
| title_fullStr | Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects |
| title_full_unstemmed | Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects |
| title_short | Synthetic biodegradable polymer materials in the repair of tumor-associated bone defects |
| title_sort | synthetic biodegradable polymer materials in the repair of tumor associated bone defects |
| topic | synthetic degradable polymer materials bone defect repair |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1096525/full |
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