Calculation of Permeability Coefficients from Solute Equilibration Dynamics: An Assessment of Various Methods

Predicting the rate at which substances permeate membrane barriers in vivo is crucial for drug development. Permeability coefficients obtained from in vitro studies are valuable for this goal. These are normally determined by following the dynamics of solute equilibration between two membrane-separa...

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Bibliographic Details
Main Authors: Margarida M. Cordeiro, Armindo Salvador, Maria João Moreno
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/12/3/254

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