Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women
Background and Purpose: Ankylosing spondylitis (AS) is an inflammatory disease that mainly affects axial skeleton of the body, and its prevalence in men is 2 to 3 times more than that in women. The difference in clinical presentations of AS in men and women is indicative of potential effect of gende...
| Format: | Article |
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| Language: | fas |
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Tehran University of Medical Sciences
2016-10-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://tumj.tums.ac.ir/browse.php?a_code=A-10-1959-2&slc_lang=en&sid=1 |
| _version_ | 1819315391174803456 |
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| collection | DOAJ |
| description | Background and Purpose: Ankylosing spondylitis (AS) is an inflammatory disease that mainly affects axial skeleton of the body, and its prevalence in men is 2 to 3 times more than that in women. The difference in clinical presentations of AS in men and women is indicative of potential effect of gender on severity of the disease. This study was conducted with the aim to investigate the effect of gender on severity of AS.
Materials and Methods: In this cross-sectional study, 115 patients with AS, comprising 88 men (76.5 %) and 27 women (23.4 %) were evaluated. Sampling was performed using non-random convenient method. The most important variables studied included clinical presentation, radiographic stage of sacroiliac involvement, and laboratory data extracted from patients’ files and recorded in questionnaires. Data were analyzed using SPSS-16 software.
Results: No significant difference was seen between men and women in age at diagnosis, entheses involvement (enthesitis), peripheral joint involvement, and laboratory data such as C-reactive protein (CRP), Erythrocyte Sedimentation Rate (ESR), and hemoglobin. Inflammatory neck pain was more prevalent in men than in women (77.2% against 51.8%; P<0.05).Sacroiliac radiographic study revealed stage 1 involvement in 11.3% of men and 37% of women (P=0.009), and stage 4 in 27.2% of men and 3.7% of women (P<0.001), with a significant difference.
Conclusion: According to the results, inflammatory neck pain and advance stage of sacroiliitis were more prevalent in men than women. |
| first_indexed | 2024-12-24T09:59:21Z |
| format | Article |
| id | doaj.art-e8e8414a31ff455baa5c59941e8ca1d7 |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-24T09:59:21Z |
| publishDate | 2016-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-e8e8414a31ff455baa5c59941e8ca1d72022-12-21T17:01:10ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222016-10-0174700Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women01234 Background and Purpose: Ankylosing spondylitis (AS) is an inflammatory disease that mainly affects axial skeleton of the body, and its prevalence in men is 2 to 3 times more than that in women. The difference in clinical presentations of AS in men and women is indicative of potential effect of gender on severity of the disease. This study was conducted with the aim to investigate the effect of gender on severity of AS. Materials and Methods: In this cross-sectional study, 115 patients with AS, comprising 88 men (76.5 %) and 27 women (23.4 %) were evaluated. Sampling was performed using non-random convenient method. The most important variables studied included clinical presentation, radiographic stage of sacroiliac involvement, and laboratory data extracted from patients’ files and recorded in questionnaires. Data were analyzed using SPSS-16 software. Results: No significant difference was seen between men and women in age at diagnosis, entheses involvement (enthesitis), peripheral joint involvement, and laboratory data such as C-reactive protein (CRP), Erythrocyte Sedimentation Rate (ESR), and hemoglobin. Inflammatory neck pain was more prevalent in men than in women (77.2% against 51.8%; P<0.05).Sacroiliac radiographic study revealed stage 1 involvement in 11.3% of men and 37% of women (P=0.009), and stage 4 in 27.2% of men and 3.7% of women (P<0.001), with a significant difference. Conclusion: According to the results, inflammatory neck pain and advance stage of sacroiliitis were more prevalent in men than women.http://tumj.tums.ac.ir/browse.php?a_code=A-10-1959-2&slc_lang=en&sid=1Keywords: Ankylosing spondylitis clinical protests Sex |
| spellingShingle | Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women Tehran University Medical Journal Keywords: Ankylosing spondylitis clinical protests Sex |
| title | Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women |
| title_full | Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women |
| title_fullStr | Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women |
| title_full_unstemmed | Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women |
| title_short | Differences in Clinical Presentation of Ankylosing Spondylitis in Men and Women |
| title_sort | differences in clinical presentation of ankylosing spondylitis in men and women |
| topic | Keywords: Ankylosing spondylitis clinical protests Sex |
| url | http://tumj.tums.ac.ir/browse.php?a_code=A-10-1959-2&slc_lang=en&sid=1 |