Small-Molecule Intervention At The Dimerization Interface Of Survivin By Novel Rigidized Scaffolds

Small-Molecule Intervention At The Dimerization Interface Of Survivin By Novel Rigidized Scaffolds

Tamer M Ibrahim,1,2 Christoph Ernst,1 Andreas Lange,1 Susanne Hennig,1 Frank M Boeckler1 1Laboratory for Molecular Design and Pharmaceutical Biophysics, Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmacy, Eberhard Karls University Tübingen, Tübingen, German...

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Bibliographic Details
Main Authors: Ibrahim TM, Ernst C, Lange A, Hennig S, Boeckler FM
Format: Article
Language:English
Published: Dove Medical Press 2019-12-01
Series:Drug Design, Development and Therapy
Subjects:
pyridin-2(1h)-one derivatives
one-pot synthesis
molecular dynamics and design
survivin dimerization modulators.
Online Access:https://www.dovepress.com/small-molecule-intervention-at-the-dimerization-interface-of-survivin--peer-reviewed-article-DDDT

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https://www.dovepress.com/small-molecule-intervention-at-the-dimerization-interface-of-survivin--peer-reviewed-article-DDDT

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